Fig. 6

Nek2 expression level was elevated in HCC patients and associated with prognosis. a. A dot plot showed the mRNA expression levels of Nek2 in HCC tissues from TCGA cohort. b. (Upper panel) A dot plot showed the protein levels of 29 pairs of HCC tissues. (Bottom panel) Four pairs of HCC tissues displayed as representative examples. c. (Upper panel) A representative results of immunohistochemistry showing the expression of Nek2 in tumor tissues and paired non-tumor tissue. (Bottom panel) Statistical analysis for 102 paired non-tumor and tumor paraffin-embedded HCC tissues. d, e. Kaplan-Meier survival analysis for overall survival of TCGA cohort (d) and 102 pairs of paraffin-embedded HCC tissues (e) according to the expression level of Nek2. Data were presented as mean ± SEM, *P<0.05; **P<0.01; ***P<0.001