Table 1 Relationship between PTBP3 expression and clinicopathological features of CRC patients
From: PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α
Variables | PTBP3 expression (n = 479 cases) | ||
|---|---|---|---|
Low | High | P a | |
All patients | 311 | 168 | |
Age (years) | 0.081 | ||
≤ 60 | 139 | 61 | |
> 60 | 172 | 107 | |
Gender | 0.495 | ||
Males | 189 | 96 | |
Females | 122 | 72 | |
Depth of invasion | 0.032* | ||
T1/T2 | 72 | 25 | |
T3/T4 | 239 | 143 | |
Lymph node metastasis | 0.074 | ||
N0 | 206 | 97 | |
N1/N2/N3 | 105 | 71 | |
Distant metastasis | 0.347 | ||
M0 | 300 | 159 | |
M1 | 11 | 9 | |
TNM stage | < 0.0001*** | ||
I/II | 168 | 47 | |
III/ IV | 143 | 121 | |
Tumor diameter | 0.250 | ||
<5 cm | 162 | 97 | |
≥ 5 cm | 149 | 71 | |
Differentiation | 0.437 | ||
Poor | 47 | 30 | |
Moderate/high | 264 | 138 | |