Fig. 7
From: Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells
Exosomal p-STAT3 derived from RKO/R cells induce 5-FU resistance in RKO/P cells in vivo. a. Flowchart of mice experiment. b. Tumors picture from mice treated with DP (DMSO + Exo/P), DR (DMSO + Exo/R), SP (stattic + Exo/P), SR (stattic + Exo/R). c. Tumor growth curves of mice treated with DP (DMSO + Exo/P), DR (DMSO + Exo/R), SP (stattic + Exo/P), SR (stattic + Exo/R). Treatment started on Day 9 and tumor volumes was measured every 2 days. d. The tumor weights from mice treated with DP (DMSO + Exo/P), DR (DMSO + Exo/R), SP (stattic + Exo/P), SR (stattic + Exo/R). e. The curves of body weights of mice treated with DP (DMSO + Exo/P), DR (DMSO + Exo/R), SP (stattic + Exo/P), SR (stattic + Exo/R). (n = 4, *P < 0.05)