Fig. 1

Screening of PTC-related circRNAs using multiple microarrays and bioinformatics. Hierarchical clustering analysis and volcano plots of significantly differentially expressed circRNAs in the invasive tumor vs. adjacent normal tissue set (a) and the invasive vs. non-invasive tumor set (b). c, d The Venn diagrams demonstrated the significantly changed circRNAs that overlapped in the foregoing comparison in PTC