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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: RETRACTED ARTICLE: Receptor tyrosine kinase inhibitor Sunitinib and integrin antagonist peptide HM-3 show similar lipid raft dependent biphasic regulation of tumor angiogenesis and metastasis

Fig. 2

Effects of Sunitinib and HM-3 on experimental B16F10 cell metastasis. a Treatment protocol of C57BL/6 mice after B16F10 cells were injected via the tail vein. b Excised lungs from the experimental B16F10 cell metastasis model were scored visually for surface tumor nodules. c Representative images of lungs from different groups at day 17 following tumor implantation. d Representative examples of micrometastases in lung by H and E staining (indicated by words in red) and anti-CD34 immunostaining (indicated by words in blue). e Statistical analysis of blood vessel numbers. Results are expressed as mean ± SD (15 regions of three sections per group. *P < 0.05, **P < 0.01 vs. control)

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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