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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Long non-coding RNA GAS5 inhibits DDP-resistance and tumor progression of epithelial ovarian cancer via GAS5-E2F4-PARP1-MAPK axis

Fig. 1

LncRNA GAS5 was down-regulated in EOC tissues and OC cell lines, and associated with EOC prognosis. a Hierarchical clustering of Agilent lncRNA array result showing abnormal expressed lncRNAs in normal ovarian or EOC tumor tissues. GAS5 is one of the most low-expressed lncRNAs in EOC tissues. b Total RNA was extracted from human normal ovarian tissues (Normal) of 10 participants and EOC tumor tissues (OC Tissues) of 53 patients, GAS5 expression levels were then detected by RT-qPCR assay. c GAS5 expression levels in OC cell lines and normal human ovarian epithelial cell line were detected by RT-qPCR assay. d Kaplan–Meier overall survival curves (OS) and disease-free survival curves (DFS) was observed based on GAS5 level. Data were the means±SD of triplicate determinants. *P < 0.05 versus control groups. **P < 0.005 versus control groups

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