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Table 3 The IC50 for paclitaxel and sorafenib

From: KIFC1 is activated by TCF-4 and promotes hepatocellular carcinoma pathogenesis by regulating HMGA1 transcriptional activity

 

IC50

Drug

Cell type

24 h

48 h

Paclitaxel (μg/ml)

7701-KIFC1-shnc

370.70

152.60

7701-KIFC1-sh33

132.30

57.22

7402-KIFC1-shnc

679.40

213.7

7402-KIFC1-sh33

334.80

75.81

HepG2-vector

31.45

7.73

HepG2-KIFC1

39.84

13.66

Sorafenib (μM)

7701-KIFC1-shnc

31.02

5.93

7701-KIFC1-sh33

29.25

6.32

7402-KIFC1-shnc

32.80

7.19

7402-KIFC1-sh33

27.76

5.21