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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: RETRACTED ARTICLE: Long non-coding RNA MACC1-AS1 promoted pancreatic carcinoma progression through activation of PAX8/NOTCH1 signaling pathway

Fig. 6

MACC1-AS1 activated NOTCH1 signaling and promoted glycolysis by PAX8. a the NOTCH1 pathway was activated by MACC1-AS1 via PAX8. b MACC1-AS1 induced NOTCH1 phosphorylation in PC cells via PAX8. c downstream elements of the NOTCH1 pathway were activated by MACC1-AS1 via PAX8. d-e the lactate production and pyruvate kinase activity were facilitated by MACC1-AS1 via modulating PAX8 in the KP-2 cell. f-g ECAR and OCR were promoted by MACC1-AS1 via modulating PAX8 in the KP-2 cell. P < 0.05, P < 0.01

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