Table 2 Cox proportional hazard models for prognostic factors
| Â | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR(95% CI) | P value | HR(95% CI) | P value | |
Age (> 60 vs. ≤60) | 1.371 (0.749–2.510) | 0.306 |  |  |
Gender (famale vs. male) | 0.874 (0.491–1.557) | 0.648 |  |  |
Tumor size (≥2 vs. < 2) | 1.502 (0.836–2.699) | 0.173 |  |  |
Tumor differentiation (Poor vs. Well) | 1.287 (0.738–2.244) | 0.375 |  |  |
TNM stage (III + IV vs. I + II) | 3.013 (1.495–6.073) | 0.002** | 3.043 (1.542–6.004) | 0.001** |
Lymph node metastasis (Positive vs. Negative) | 2.109 (1.151–3.864) | 0.016* | 1.873 (1.100–3.188) | 0.021* |
Distant metastasis (M1 vs. M0) | 1.244 (0.679–2.280) | 0.479 |  |  |
ANLN expression (high vs. low) | 1.923 (1.051–3.521) | 0.034* | 2.352 (1.369–4.039) | 0.002** |