Fig. 9

The interaction of suv39h1 with MeCP2 mediated miR-200c. a-b Endogenous MeCP2 co-immunoprecipitated with endogenous suv39h1 was observed by co-immunoprecipitation analysis. c-d ChIP-PCR shows that overexpression of MeCP2 led to an increase of suv39h1 bound to miR-200c. *P < 0.05, **P < 0.01 vs. vector. e-f ChIP was performed to analyze H3K9 occupancy at the miR-200c promoter in glioma cells transfected with si-NC and si-Suv39h1. **P < 0.01 vs. vector. g expression of miR-200c was examined in glioma cells transfected with si-NC and si-Suv39h1. **P < 0.01 vs. vector