Fig. 1

The different expression and survival of patients of CRABP2 in ER⁺ and ER⁻ breast cancer. a-b Representative pictures of CRABP2 in human ER⁺ (a) and ER⁻ (b) breast cancer tissues and the neighboring non-cancerous tissues with immunohistochemical staining. Scalebar, 145 μm, 73 μm. P-values were calculated by the Student’s t-test. c Compiled results of CRABP2 immunohistochemical staining performed on human ER⁺ and ER⁻ BRCA samples. Scalebar, 145 μm, 73 μm. P-values were calculated by the Student’s t-test. d-e Kaplan Meier survival curve of CRABP2 expression respectively in ER⁺ (d) and ER⁻ (e) mammary cancer. P-values were calculated by the log-rank test. f-g Expression of CRABP2 protein (f) and mRNA (g) was examined in 5 kinds of cells by Western blotting and RT-qPCR. Data are the mean ± S.D. of three independent experiments performed in triplicate. *, P < 0.05; **, P < 0.01; ***, P < 0.001