TY - JOUR AU - Koul, H. AU - Huh, J. S. AU - Rove, K. O. AU - Crompton, L. AU - Koul, S. AU - Meacham, R. B. PY - 2011 DA - 2011// TI - Molecular aspects of renal cell carcinoma: a review JO - Am J Cancer Res VL - 1 ID - Koul2011 ER - TY - JOUR AU - Sanchez-Gastaldo, A. AU - Kempf, E. AU - Gonzalez Del Alba, A. AU - Duran, I. PY - 2017 DA - 2017// TI - Systemic treatment of renal cell cancer: a comprehensive review JO - Cancer Treat Rev VL - 60 UR - https://doi.org/10.1016/j.ctrv.2017.08.010 DO - 10.1016/j.ctrv.2017.08.010 ID - Sanchez-Gastaldo2017 ER - TY - JOUR AU - Stukalin, I. AU - Alimohamed, N. AU - Heng, D. Y. PY - 2016 DA - 2016// TI - Contemporary treatment of metastatic renal cell carcinoma JO - Oncol Rev VL - 10 UR - https://doi.org/10.4081/oncol.2016.295 DO - 10.4081/oncol.2016.295 ID - Stukalin2016 ER - TY - JOUR AU - Hutson, T. E. PY - 2011 DA - 2011// TI - Targeted therapies for the treatment of metastatic renal cell carcinoma: clinical evidence JO - Oncologist. VL - 16 UR - https://doi.org/10.1634/theoncologist.2011-S2-14 DO - 10.1634/theoncologist.2011-S2-14 ID - Hutson2011 ER - TY - JOUR AU - Charlesworth, P. J. AU - Harris, A. L. PY - 2006 DA - 2006// TI - Mechanisms of disease: angiogenesis in urologic malignancies JO - Nat Clin Pract Urol VL - 3 UR - https://doi.org/10.1038/ncpuro0434 DO - 10.1038/ncpuro0434 ID - Charlesworth2006 ER - TY - JOUR AU - Schraml, P. AU - Struckmann, K. AU - Hatz, F. AU - Sonnet, S. AU - Kully, C. AU - Gasser, T. PY - 2002 DA - 2002// TI - VHL mutations and their correlation with tumour cell proliferation, microvessel density, and patient prognosis in clear cell renal cell carcinoma JO - J Pathol VL - 196 UR - https://doi.org/10.1002/path.1034 DO - 10.1002/path.1034 ID - Schraml2002 ER - TY - JOUR AU - Escudier, B. AU - Eisen, T. AU - Stadler, W. M. AU - Szczylik, C. AU - Oudard, S. AU - Siebels, M. PY - 2007 DA - 2007// TI - Sorafenib in advanced clear-cell renal-cell carcinoma JO - N Engl J Med VL - 356 UR - https://doi.org/10.1056/NEJMoa060655 DO - 10.1056/NEJMoa060655 ID - Escudier2007 ER - TY - JOUR AU - Bielecka, Z. F. AU - Czarnecka, A. M. AU - Solarek, W. AU - Kornakiewicz, A. AU - Szczylik, C. PY - 2014 DA - 2014// TI - Mechanisms of acquired resistance to tyrosine kinase inhibitors in clear - cell renal cell carcinoma (ccRCC) JO - Curr Signal Transduct Ther VL - 8 UR - https://doi.org/10.2174/1574362409666140206223014 DO - 10.2174/1574362409666140206223014 ID - Bielecka2014 ER - TY - JOUR AU - Mao, J. AU - Yang, H. AU - Cui, T. AU - Pan, P. AU - Kabir, N. AU - Chen, D. PY - 2018 DA - 2018// TI - Combined treatment with sorafenib and silibinin synergistically targets both HCC cells and cancer stem cells by enhanced inhibition of the phosphorylation of STAT3/ERK/AKT JO - Eur J Pharmacol VL - 832 UR - https://doi.org/10.1016/j.ejphar.2018.05.027 DO - 10.1016/j.ejphar.2018.05.027 ID - Mao2018 ER - TY - JOUR AU - Blivet-Van Eggelpoel, M. J. AU - Chettouh, H. AU - Fartoux, L. AU - Aoudjehane, L. AU - Barbu, V. AU - Rey, C. PY - 2012 DA - 2012// TI - Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells JO - J Hepatol VL - 57 UR - https://doi.org/10.1016/j.jhep.2012.02.019 DO - 10.1016/j.jhep.2012.02.019 ID - Blivet-Van Eggelpoel2012 ER - TY - JOUR AU - Ravaud, A. AU - Gross-Goupil, M. AU - Bellmunt, J. PY - 2013 DA - 2013// TI - Combination therapy in metastatic renal cell cancer JO - Semin Oncol VL - 40 UR - https://doi.org/10.1053/j.seminoncol.2013.05.010 DO - 10.1053/j.seminoncol.2013.05.010 ID - Ravaud2013 ER - TY - JOUR AU - Rini, B. I. AU - Atkins, M. B. PY - 2009 DA - 2009// TI - Resistance to targeted therapy in renal-cell carcinoma JO - Lancet Oncol VL - 10 UR - https://doi.org/10.1016/S1470-2045(09)70240-2 DO - 10.1016/S1470-2045(09)70240-2 ID - Rini2009 ER - TY - JOUR AU - Xin, H. W. AU - Ambe, C. M. AU - Miller, T. C. AU - Chen, J. Q. AU - Wiegand, G. W. AU - Anderson, A. J. PY - 2016 DA - 2016// TI - Liver label retaining Cancer cells are relatively resistant to the reported anti-Cancer stem cell drug metformin JO - J Cancer VL - 7 UR - https://doi.org/10.7150/jca.10047 DO - 10.7150/jca.10047 ID - Xin2016 ER - TY - JOUR AU - Pan, H. AU - Wang, Z. AU - Jiang, L. AU - Sui, X. AU - You, L. AU - Shou, J. PY - 2014 DA - 2014// TI - Autophagy inhibition sensitizes hepatocellular carcinoma to the multikinase inhibitor linifanib JO - Sci Rep VL - 4 UR - https://doi.org/10.1038/srep06683 DO - 10.1038/srep06683 ID - Pan2014 ER - TY - JOUR AU - Xin, H. W. AU - Ambe, C. M. AU - Hari, D. M. AU - Wiegand, G. W. AU - Miller, T. C. AU - Chen, J. Q. PY - 2013 DA - 2013// TI - Label-retaining liver cancer cells are relatively resistant to sorafenib JO - Gut. VL - 62 UR - https://doi.org/10.1136/gutjnl-2012-303261 DO - 10.1136/gutjnl-2012-303261 ID - Xin2013 ER - TY - JOUR AU - Hagiwara, S. AU - Kudo, M. AU - Nagai, T. AU - Inoue, T. AU - Ueshima, K. AU - Nishida, N. PY - 2012 DA - 2012// TI - Activation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinoma JO - Br J Cancer VL - 106 UR - https://doi.org/10.1038/bjc.2012.145 DO - 10.1038/bjc.2012.145 ID - Hagiwara2012 ER - TY - JOUR AU - Matsumoto, K. AU - Nakamura, T. PY - 1991 DA - 1991// TI - Hepatocyte growth factor: molecular structure and implications for a central role in liver regeneration JO - J Gastroenterol Hepatol VL - 6 UR - https://doi.org/10.1111/j.1440-1746.1991.tb00897.x DO - 10.1111/j.1440-1746.1991.tb00897.x ID - Matsumoto1991 ER - TY - JOUR AU - Bottaro, D. P. AU - Rubin, J. S. AU - Faletto, D. L. AU - Chan, A. M. AU - Kmiecik, T. E. AU - Vande Woude, G. F. PY - 1991 DA - 1991// TI - Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product JO - Science. VL - 251 UR - https://doi.org/10.1126/science.1846706 DO - 10.1126/science.1846706 ID - Bottaro1991 ER - TY - JOUR AU - Xin, L. AU - Xu, R. AU - Zhang, Q. AU - Li, T. P. AU - Gan, R. B. PY - 2000 DA - 2000// TI - Kringle 1 of human hepatocyte growth factor inhibits bovine aortic endothelial cell proliferation stimulated by basic fibroblast growth factor and causes cell apoptosis JO - Biochem Biophys Res Commun VL - 277 UR - https://doi.org/10.1006/bbrc.2000.3658 DO - 10.1006/bbrc.2000.3658 ID - Xin2000 ER - TY - JOUR AU - Yao, Y. AU - Fang, Z. P. AU - Chen, H. AU - Yue, L. AU - Min, D. I. AU - Tang, L. N. PY - 2012 DA - 2012// TI - HGFK1 inhibits bone metastasis in breast cancer through the TAK1/p38 MAPK signaling pathway JO - Cancer Gene Ther VL - 19 UR - https://doi.org/10.1038/cgt.2012.38 DO - 10.1038/cgt.2012.38 ID - Yao2012 ER - TY - JOUR AU - Nie, B. AU - Shen, Z. AU - Wen, J. B. AU - Wong, O. G. W. AU - Hsueh, W. D. AU - Huo, L. F. PY - 2008 DA - 2008// TI - AAV-HGFK1 and ad-p53 cocktail therapy prolongs survival of mice with colon cancer JO - Mol Cancer Ther VL - 7 UR - https://doi.org/10.1158/1535-7163.MCT-08-0366 DO - 10.1158/1535-7163.MCT-08-0366 ID - Nie2008 ER - TY - JOUR AU - Zan, S. AU - Zhen, F. Y. AU - Yi, G. AU - Ji, C. L. AU - Hai, X. C. AU - Ching, C. L. PY - 2008 DA - 2008// TI - The Kringle 1 domain of hepatocyte growth factor has antiangiogenic and antitumor cell effects on hepatocellular carcinoma JO - Cancer Res VL - 68 UR - https://doi.org/10.1158/0008-5472.CAN-07-2081 DO - 10.1158/0008-5472.CAN-07-2081 ID - Zan2008 ER - TY - JOUR AU - Shen, Z. AU - Wong, O. G. W. AU - Yao, R. Y. AU - Liang, J. AU - Kung, H. F. AU - Lin, M. C. M. PY - 2008 DA - 2008// TI - A novel and effective hepatocyte growth factor kringle 1 domain and p53 cocktail viral gene therapy for the treatment of hepatocellular carcinoma JO - Cancer Lett VL - 272 UR - https://doi.org/10.1016/j.canlet.2008.03.064 DO - 10.1016/j.canlet.2008.03.064 ID - Shen2008 ER - TY - JOUR AU - Zhang, W. AU - Duan, R. AU - Zhang, J. AU - Cheung, W. K. C. AU - Gao, X. AU - Zhang, R. PY - 2018 DA - 2018// TI - H1/pHGFK1 nanoparticles exert anti-tumoural and radiosensitising effects by inhibition of MET in glioblastoma JO - Br J Cancer VL - 118 UR - https://doi.org/10.1038/bjc.2017.461 DO - 10.1038/bjc.2017.461 ID - Zhang2018 ER - TY - JOUR AU - Yao, H. AU - Ng, S. S. AU - Huo, L. F. AU - Chow, B. K. AU - Shen, Z. AU - Yang, M. PY - 2011 DA - 2011// TI - Effective melanoma immunotherapy with interleukin-2 delivered by a novel polymeric nanoparticle JO - Mol Cancer Ther VL - 10 UR - https://doi.org/10.1158/1535-7163.MCT-10-0717 DO - 10.1158/1535-7163.MCT-10-0717 ID - Yao2011 ER - TY - JOUR AU - Yao, H. AU - Ng, S. S. AU - Tucker, W. O. AU - Tsang, Y. K. AU - Man, K. AU - Wang, X. M. PY - 2009 DA - 2009// TI - The gene transfection efficiency of a folate-PEI600-cyclodextrin nanopolymer JO - Biomaterials. VL - 30 UR - https://doi.org/10.1016/j.biomaterials.2009.06.051 DO - 10.1016/j.biomaterials.2009.06.051 ID - Yao2009 ER - TY - JOUR AU - Suk, J. S. AU - Xu, Q. AU - Kim, N. AU - Hanes, J. AU - Ensign, L. M. PY - 2016 DA - 2016// TI - PEGylation as a strategy for improving nanoparticle-based drug and gene delivery JO - Adv Drug Deliv Rev VL - 99 UR - https://doi.org/10.1016/j.addr.2015.09.012 DO - 10.1016/j.addr.2015.09.012 ID - Suk2016 ER - TY - JOUR AU - Shaw, F. L. AU - Harrison, H. AU - Spence, K. AU - Ablett, M. P. AU - Simoes, B. M. AU - Farnie, G. PY - 2012 DA - 2012// TI - A detailed mammosphere assay protocol for the quantification of breast stem cell activity JO - J Mammary Gland Biol Neoplasia VL - 17 UR - https://doi.org/10.1007/s10911-012-9255-3 DO - 10.1007/s10911-012-9255-3 ID - Shaw2012 ER - TY - JOUR AU - Gunther, K. AU - Mertig, M. AU - Seidel, R. PY - 2010 DA - 2010// TI - Mechanical and structural properties of YOYO-1 complexed DNA JO - Nucleic Acids Res VL - 38 UR - https://doi.org/10.1093/nar/gkq434 DO - 10.1093/nar/gkq434 ID - Gunther2010 ER - TY - JOUR AU - Gerdes, J. PY - 1990 DA - 1990// TI - Ki-67 and other proliferation markers useful for immunohistological diagnostic and prognostic evaluations in human malignancies JO - Semin Cancer Biol VL - 1 ID - Gerdes1990 ER - TY - JOUR AU - Noda, N. N. AU - Inagaki, F. PY - 2015 DA - 2015// TI - Mechanisms of autophagy JO - Annu Rev Biophys VL - 44 UR - https://doi.org/10.1146/annurev-biophys-060414-034248 DO - 10.1146/annurev-biophys-060414-034248 ID - Noda2015 ER - TY - JOUR AU - Yang, M. C. AU - Wang, H. C. AU - Hou, Y. C. AU - Tung, H. L. AU - Chiu, T. J. AU - Shan, Y. S. PY - 2015 DA - 2015// TI - Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine JO - Mol Cancer VL - 14 UR - https://doi.org/10.1186/s12943-015-0449-3 DO - 10.1186/s12943-015-0449-3 ID - Yang2015 ER - TY - JOUR AU - Dawood, S. AU - Austin, L. AU - Cristofanilli, M. PY - 2014 DA - 2014// TI - Cancer stem cells: implications for cancer therapy JO - Oncology (Williston Park) VL - 28 ID - Dawood2014 ER - TY - JOUR AU - Wu, G. AU - Wilson, G. AU - Zhou, G. AU - Hebbard, L. AU - George, J. AU - Qiao, L. PY - 2015 DA - 2015// TI - Oct4 is a reliable marker of liver tumor propagating cells in hepatocellular carcinoma JO - Discov Med VL - 20 ID - Wu2015 ER - TY - JOUR AU - Jeter, C. R. AU - Liu, B. AU - Liu, X. AU - Chen, X. AU - Liu, C. AU - Calhoun-Davis, T. PY - 2011 DA - 2011// TI - NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation JO - Oncogene. VL - 30 UR - https://doi.org/10.1038/onc.2011.114 DO - 10.1038/onc.2011.114 ID - Jeter2011 ER - TY - JOUR AU - Trocoli, A. AU - Djavaheri-Mergny, M. PY - 2011 DA - 2011// TI - The complex interplay between autophagy and NF-kappaB signaling pathways in cancer cells JO - Am J Cancer Res VL - 1 ID - Trocoli2011 ER - TY - JOUR AU - Wu, J. M. AU - Sheng, H. AU - Saxena, R. AU - Skill, N. J. AU - Bhat-Nakshatri, P. AU - Yu, M. PY - 2009 DA - 2009// TI - NF-kappaB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy JO - Cancer Lett VL - 278 UR - https://doi.org/10.1016/j.canlet.2008.12.031 DO - 10.1016/j.canlet.2008.12.031 ID - Wu2009 ER - TY - JOUR AU - Wilhelm, S. M. AU - Adnane, L. AU - Newell, P. AU - Villanueva, A. AU - Llovet, J. M. AU - Lynch, M. PY - 2008 DA - 2008// TI - Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling JO - Mol Cancer Ther VL - 7 UR - https://doi.org/10.1158/1535-7163.MCT-08-0013 DO - 10.1158/1535-7163.MCT-08-0013 ID - Wilhelm2008 ER - TY - JOUR AU - Li, Y. AU - Gao, Z. H. AU - Qu, X. J. PY - 2015 DA - 2015// TI - The adverse effects of sorafenib in patients with advanced cancers JO - Basic Clin Pharmacol Toxicol VL - 116 UR - https://doi.org/10.1111/bcpt.12365 DO - 10.1111/bcpt.12365 ID - Li2015 ER - TY - JOUR AU - Berasain, C. PY - 2013 DA - 2013// TI - Hepatocellular carcinoma and sorafenib: too many resistance mechanisms? JO - Gut. VL - 62 UR - https://doi.org/10.1136/gutjnl-2013-304564 DO - 10.1136/gutjnl-2013-304564 ID - Berasain2013 ER - TY - JOUR AU - Lobo, N. A. AU - Shimono, Y. AU - Qian, D. AU - Clarke, M. F. PY - 2007 DA - 2007// TI - The biology of cancer stem cells JO - Annu Rev Cell Dev Biol VL - 23 UR - https://doi.org/10.1146/annurev.cellbio.22.010305.104154 DO - 10.1146/annurev.cellbio.22.010305.104154 ID - Lobo2007 ER - TY - JOUR AU - Dean, M. AU - Fojo, T. AU - Bates, S. PY - 2005 DA - 2005// TI - Tumour stem cells and drug resistance JO - Nat Rev Cancer VL - 5 UR - https://doi.org/10.1038/nrc1590 DO - 10.1038/nrc1590 ID - Dean2005 ER - TY - JOUR AU - Hu, X. AU - Ghisolfi, L. AU - Keates, A. C. AU - Zhang, J. AU - Xiang, S. AU - Lee, D. K. PY - 2012 DA - 2012// TI - Induction of cancer cell stemness by chemotherapy JO - Cell Cycle VL - 11 UR - https://doi.org/10.4161/cc.21021 DO - 10.4161/cc.21021 ID - Hu2012 ER - TY - JOUR AU - Gupta, P. B. AU - Fillmore, C. M. AU - Jiang, G. AU - Shapira, S. D. AU - Tao, K. AU - Kuperwasser, C. PY - 2011 DA - 2011// TI - Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells JO - Cell. VL - 146 UR - https://doi.org/10.1016/j.cell.2011.07.026 DO - 10.1016/j.cell.2011.07.026 ID - Gupta2011 ER - TY - JOUR AU - Li, Y. AU - Rogoff, H. A. AU - Keates, S. AU - Gao, Y. AU - Murikipudi, S. AU - Mikule, K. PY - 2015 DA - 2015// TI - Suppression of cancer relapse and metastasis by inhibiting cancer stemness JO - Proc Natl Acad Sci U S A VL - 112 UR - https://doi.org/10.1073/pnas.1424171112 DO - 10.1073/pnas.1424171112 ID - Li2015 ER - TY - JOUR AU - Doria, A. AU - Gatto, M. AU - Punzi, L. PY - 2013 DA - 2013// TI - Autophagy in human health and disease JO - N Engl J Med VL - 368 UR - https://doi.org/10.1056/NEJMc1303158 DO - 10.1056/NEJMc1303158 ID - Doria2013 ER - TY - JOUR AU - White, E. PY - 2015 DA - 2015// TI - The role for autophagy in cancer JO - J Clin Invest VL - 125 UR - https://doi.org/10.1172/JCI73941 DO - 10.1172/JCI73941 ID - White2015 ER - TY - JOUR AU - Jiang, X. AU - Overholtzer, M. AU - Thompson, C. B. PY - 2015 DA - 2015// TI - Autophagy in cellular metabolism and cancer JO - J Clin Invest VL - 125 UR - https://doi.org/10.1172/JCI73942 DO - 10.1172/JCI73942 ID - Jiang2015 ER - TY - JOUR AU - Yue, W. AU - Hamai, A. AU - Tonelli, G. AU - Bauvy, C. AU - Nicolas, V. AU - Tharinger, H. PY - 2013 DA - 2013// TI - Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance JO - Autophagy. VL - 9 UR - https://doi.org/10.4161/auto.23997 DO - 10.4161/auto.23997 ID - Yue2013 ER - TY - JOUR AU - Czyz, M. a. l. g. o. r. z. a. t. a. PY - 2018 DA - 2018// TI - HGF/c-MET Signaling in Melanocytes and Melanoma JO - International Journal of Molecular Sciences VL - 19 UR - https://doi.org/10.3390/ijms19123844 DO - 10.3390/ijms19123844 ID - Czyz2018 ER - TY - JOUR AU - Organ, S. L. AU - Tsao, M. S. PY - 2011 DA - 2011// TI - An overview of the c-MET signaling pathway JO - Ther Adv Med Oncol VL - 3 UR - https://doi.org/10.1177/1758834011422556 DO - 10.1177/1758834011422556 ID - Organ2011 ER - TY - JOUR AU - Goyal, L. AU - Muzumdar, M. D. AU - Zhu, A. X. PY - 2013 DA - 2013// TI - Targeting the HGF/c-MET pathway in hepatocellular carcinoma JO - Clin Cancer Res VL - 19 UR - https://doi.org/10.1158/1078-0432.CCR-12-2791 DO - 10.1158/1078-0432.CCR-12-2791 ID - Goyal2013 ER - TY - JOUR AU - Feng, Y. AU - Dai, X. AU - Li, X. AU - Wang, H. AU - Liu, J. AU - Zhang, J. PY - 2012 DA - 2012// TI - EGF signalling pathway regulates colon cancer stem cell proliferation and apoptosis JO - Cell Prolif VL - 45 UR - https://doi.org/10.1111/j.1365-2184.2012.00837.x DO - 10.1111/j.1365-2184.2012.00837.x ID - Feng2012 ER - TY - JOUR AU - Dvorak, P. AU - Dvorakova, D. AU - Hampl, A. PY - 2006 DA - 2006// TI - Fibroblast growth factor signaling in embryonic and cancer stem cells JO - FEBS Lett VL - 580 UR - https://doi.org/10.1016/j.febslet.2006.01.095 DO - 10.1016/j.febslet.2006.01.095 ID - Dvorak2006 ER - TY - JOUR AU - Shaheen, S. AU - Ahmed, M. AU - Lorenzi, F. AU - Nateri, A. S. PY - 2016 DA - 2016// TI - Spheroid-formation (Colonosphere) assay for in vitro assessment and expansion of stem cells in Colon Cancer JO - Stem Cell Rev VL - 12 UR - https://doi.org/10.1007/s12015-016-9664-6 DO - 10.1007/s12015-016-9664-6 ID - Shaheen2016 ER -