Fig. 8From: Peglated-H1/pHGFK1 nanoparticles enhance anti-tumor effects of sorafenib by inhibition of drug-induced autophagy and stemness in renal cell carcinomaHGFK1 suppresses sorafenib-induced cancer stemness in RCC. a Ketr-3 and ACHN cells were treated with sorafenib and/or rHGFK1 for 48 h, then analyzed the expression of CD133, Nanog, and Oct4 with Western-Blotting. b Mammosphere formation assay was used to analyze the cancer stemness of Ketr-3 and ACHN cells after treated with sorafenib and/or rHGFK1Back to article page