Fig. 9

Effect of sorafenib and HGFK1 on the expression of LC3B, phosphorylated NF-κB, CD133, Nanog, and Oct4 in vivo. Tumor tissues from sorafenib and/or HGFK1 treated tumor-bearing mice were collected and stained with IHC. The expression of LC3B and phosphorylated NF-κB (a), as well as CD133, Nanog, and Oct4 (b) on tumor tissues was analyzed and quantified with IOD. All data shown represent the mean ± SD from three to five independent sections. Significant differences are denoted by ** for p < 0.01, and *** for p < 0.001