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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Depleting PTOV1 sensitizes non-small cell lung cancer cells to chemotherapy through attenuating cancer stem cell traits

Fig. 5

Depleting PTOV1 impaired stem cell-like properties in NSCLC cells. a Representative images of tumor sphere formation of the indicated cells. b FACS analysis of the portion of CD133+ cells. c Real-time quantitative PCR detecting the expression of the pluripotency factors in the indicated cells. d Real-time quantitative PCR detecting the expression of PTOV1 and CD133 in undifferentiated and serum-induced differentiated cells. Error bars represent the mean ± SD from 3 independent experiments. *, P < 0.05; #, P < 0.01; $, P < 0.001, two-tailed, unpaired t-test

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