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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: LncRNA AFAP1-AS1 promotes tumorigenesis and epithelial-mesenchymal transition of osteosarcoma through RhoC/ROCK1/p38MAPK/Twist1 signaling pathway

Fig. 5

Knockdown of AFAP1-AS1-inhibited EMT is mediated by the Twsit1. a, b and c Overexpression of Twist1 in AFAP1-AS1 knockdown OS cells could rescue AFAP1-AS1 downregulation-induced inhibition of cell migration, invasion and EMT. d and e Both downregulating AFAP1-AS1 and Twist1, EMT of OS cells were inhibited further. *P < 0.05, **P < 0.01, ***P < 0.001

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