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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: LncRNA LINC00460 promotes EMT in head and neck squamous cell carcinoma by facilitating peroxiredoxin-1 into the nucleus

Fig. 6

PRDX1 mediated the function of LINC00460 to promote the proliferation and metastasis of HNSCC cells. a, b The growth curves were detected by CCK-8 assay when PRDX1 was knocked down in CAL-27 cells stably transduced with LINC00460 (a) and when LINC00460 was knocked down in CAL-27 cells stably transduced with PRDX1 vector (b). c, d The colonizing abilities were detected by colony formation assays when PRDX1 was knocked down in CAL-27 cells stably transduced with LINC00460 (c) and when LINC00460 was knocked down in CAL-27 cells stably transduced with PRDX1 vector (d). e, f The migration abilities were assessed by transwell assays when PRDX1 was knocked down in CAL-27 cells stably transduced with LINC00460 (e) and when LINC00460 was knocked down in CAL-27 cells stably transduced with PRDX1 vector (f). *p < 0.05, ***p < 0.001, ****p < 0.0001, ns: no significance

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