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Table 1 Relationship between LINC00460 level and clinicopathologic features (N = 123)

From: LncRNA LINC00460 promotes EMT in head and neck squamous cell carcinoma by facilitating peroxiredoxin-1 into the nucleus

Characteristics No. of Patients LINC00460 ΔCta Mean ± SD Non-parametric test value p value
No. %
Age (years)
 ≥ 60 81 65.85 8.553 ± 2.175 Z = 0.277 0.782
 < 60 42 34.15 8.607 ± 2.906
Gender
 Male 84 68.29 8.645 ± 2.758 Z = 0.386 0.700
 Female 39 31.71 8.412 ± 1.555
Tumor Size (cm)
 ≤ 4 73 59.35 8.745 ± 2.548 Z = 0.608 0.543
 > 4 50 40.65 8.319 ± 2.268
Lymph Node Metastasis
 pN1 to pN3 63 51.22 8.022 ± 2.210 Z = 2.436 0.015 *
 pN0 60 48.78 9.231 ± 2.635
TNM Stage
 I 11 8.94 9.991 ± 3.331 H = 4.052 0.256
 II 28 22.76 9.087 ± 2.559
 III 19 15.45 8.147 ± 2.719
 IV 65 52.85 8.233 ± 2.028
Pathological Differentiation
 Well 85 69.11 8.810 ± 2.122 Z = 2.094 0.036 *
 Moderately/poorly 38 30.89 8.038 ± 2.990
Tumor Site
 Tongue 42 34.15 8.812 ± 1.928 H = 3.411 0.492
 Gingival 36 29.27 8.293 ± 2.304
 Cheek 25 20.32 8.122 ± 2.246
 Floor of Mouth 6 4.88 8.802 ± 1.548
 Oropharynx 14 11.38 8.775 ± 3.268
Local Invasion
 No 87 70.73 8.550 ± 2.604 Z = 0.183 0.854
 Yes 36 29.27 8.624 ± 2.011
Tumor Type
 Primary 105 85.37 8.723 ± 2.493 Z = 1.782 0.075
 Recurrence 18 14.63 7.684 ± 1.907
  1. Abbreviations: SD standard deviation, pN pathological lymph node status
  2. aThe ΔCt value was determined by subtracting the GAPDH Ct value from the LINC00460 Ct value. Smaller ΔCt values indicate higher expression. *p<0.05