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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Curcumin C3 complex®/Bioperine® has antineoplastic activity in mesothelioma: an in vitro and in vivo analysis

Fig. 3

CBP treatments induce apoptosis in mesothelioma cells. FACS analysis by Annexin V-FITC/PI double staining assay for the detection of apoptosis in MSTO, NCI and Mes-2 cells treated with 20 μM CPB for 24, 48 and 72 h. Q2 and Q4: early and late apoptotic cells; Q1: necrotic fraction; Q3: live cells. Histograms on the right report a data summary of the apoptotic index. Bars represent the average ± SD of independent experiments (n = 3). Statistically significant difference compared to untreated cells: *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001. CTRL: untreated cells

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