S1PR1 promotes proliferation and inhibits apoptosis of esophageal squamous cell carcinoma through activating STAT3 pathway

Table 1 Clinico-pathologic characteristics of ESCC patients

Characteristics	Total 127	S1PR1		χ2
Characteristics	Total 127	Low expression(65)	High expression(62)	χ2	P-value
Age
< 60	30	18	12	1.223	0.269
≥ 60	97	47	50
Gender
Male	80	38	42	1.172	0.279
Female	47	27	20
Histological grade
G3	54	19	35	10.963	0.005*
G2	44	25	19
G1	29	21	8
T classification
T1	34	23	11	6.941	0.031*
T2	48	25	23
T3	45	17	28
N classification
Absent (0)	91	55	36	11.013	< 0.01*
Present (1/2/3)	36	10	26
M classification
M0	122	63	59	0.26	0.61
M1	5	2	3
Clinical stage
I	28	21	7	8.076	0.018*
II	65	31	34
III/IV	34	13	19

ISSN: 1756-9966