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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Modulating lncRNA SNHG15/CDK6/miR-627 circuit by palbociclib, overcomes temozolomide resistance and reduces M2-polarization of glioma associated microglia in glioblastoma multiforme

Fig. 1

Increased lncSNHG15 in GBM cells and is associated with a poor prognosis. a Analysis of GBM database (GSE4290) showed that the level of lncSNHG15 was significantly higher in the GBM clinical samples as compared to the normal brain. Numbers in parentheses indicate the sample number. b In another database (GSE16581), a higher level lncSNHG15 was also identified in the patients with a higher risk for GBM. c Kaplan-Meier survival curve was drawn from the same cohort (GSE16581) and showed a higher level of lncSNHG15 was significantly associated with a lower survival ratio. The number of patients in each arm is indicated. d Using another database (GSE108476), a higher lncSNHG15 level statistically predicted a shorter survival time in the patients with glioma (N = 524)

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