Fig. 8

circPTN rescues the inhibition of GSCs self-renewal by miR-145-5p. a. Results of western blot assay showed that circPTN could rescue the inhibition of SOX9 expression by miR-145-5p. b. Images of tumor sphere formation assay (200 cells/well); scale bar, 50 μm. c. Analyses of tumor sphere formation results indicated that circPTN could rescue the inhibition of self-renewal of G15 cells by miR-145-5p, n = 10, *p < 0.05, t test. d. Results of western blot assay showed that circPTN-145-mut failed to rescue the inhibition of SOX9 expression by miR-145-5p.e. Images of tumor sphere formation assay (200 cells/well); scale bar, 50 μm. f. Analyses of tumor sphere formation results indicated that circPTN-145-mut failed to rescue the inhibition of self-renewal of G15 cells by miR-145-5p, n = 10, *p < 0.05, t test