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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Hypoxic exosomes facilitate angiogenesis and metastasis in esophageal squamous cell carcinoma through altering the phenotype and transcriptome of endothelial cells

Fig. 6

Microarray analysis revealed differentially expressed RNAs between different groups. a Scatter-Plot of differentially expressed RNAs variations between HUVECs in the control group and norm-Exo group. Dots above the top line (red) and below the bottom line (green) indicated the fold change of the RNAs is more than 1.5 between the two groups. Heat map of the dysregulated mRNA, lncRNA and circular RNA expression in control group and norm-Exo group. b Scatter-Plot of differentially expressed RNAs variations between HUVECs in the control group and hypo-Exo group. Heat map of the dysregulated mRNA, lncRNA and circular RNA expression in control group and hypo-Exo group. Eight hundred and thirty nine down-regulated mRNAs (c), 113 up-regulated mRNAs (d), 232 down-regulated lncRNAs (e), 99 up-regulated lncRNAs (f), 692 down-regulated circular RNAs (g) and 86 up-regulated circular RNAs (h) were identified according to the intersection of transcriptome between norm-Exo group and hypo-Exo group

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