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Table 2 Cox regression analysis for overall survival and recurrence-free survival

From: Cripto-1 expression in patients with clear cell renal cell carcinoma is associated with poor disease outcome

Variable

Univariate analysis

Multivariate analysis

HR

95%CI

P

HR

95%CI

P

(A) Overall survival

 T stage

  T3–4 vs T1–2

7.417

4.985–11.035

< 0.001

2.531

1.547–4.141

< 0.001

 Lymph-node status

  N1–2 vs N0

7.141

4.681–10.895

< 0.001

3.969

2.431–6.482

< 0.001

 Distant metastasis

  M1 vs M0

13.621

7.747–23.946

< 0.001

3.809

2.074–6.995

< 0.001

 Fuhrman grade

  G3–4 vs G1–2

4.594

3.067–6.883

< 0.001

1.946

1.198–3.161

0.007

 CR-1 expression

  High vs low

7.031

4.068–12.152

< 0.001

6.518

3.689–11.516

< 0.001

(B) Recurrence-free survival

 T stage

  T3–4 vs T1–2

5.380

3.409–8.490

< 0.001

2.051

1.167–3.606

0.013

 Lymph-node status

  N1–2 vs N0

6.320

3.836–10.410

< 0.001

4.818

2.581–8.995

< 0.001

 Fuhrman grade

  G3–4 vs G1–2

3.685

2.302–5.897

< 0.001

1.783

1.045–3.043

0.034

 CR-1 expression

  High vs low

5.133

3.058–8.616

< 0.001

5.638

3.274–9.711

< 0.001

  1. Abbreviations: HR Hazard ratio, 95% CI 95% confidence interval
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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