Fig. 1

IL-6 is highly expressed in OC and positively associate PD-L1 in neutrophils. a The number of neutrophils in peripheral blood of OC patients and normal controls as determined by flow cytometry. b The expression of PD-L1 in infiltrated neutrophils and neutrophils from peripheral blood of OC patients as measured by flow cytometry. c The correlation between IL-6 expression in peripheral blood as detected by RT-qPCR and PD-L1 expression in infiltrated neutrophils as determined by flow cytometry analyzed by Pearson’s correlation coefficient. d The expression of IL-6 in OC tissues as detected by immunohistochemical staining (400 ×). e The Pearson’s correlation analysis between IL-6 expression determined by immunohistochemical staining and PD-L1 expression in infiltrated neutrophils determined by flow cytometry. ^* p < 0.05 vs. normal controls; ^# p < 0.05 vs. the neutrophils in peripheral blood; ^& p < 0.05 vs. the IL-6 (−/+). The measurement data were summarized as mean ± standard deviation. The unpaired t test was used to compare the data between two groups. The experiment was repeated 3 times independently