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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Long non-coding RNA HOTTIP enhances IL-6 expression to potentiate immune escape of ovarian cancer cells by upregulating the expression of PD-L1 in neutrophils

Fig. 6

Overexpression of HOTTIP in OC tissues enhances the expression of PD-L1 in neutrophils. a HOTTIP expression in OC tissues and normal fallopian tube fimbriae tissues as determined by RT-qPCR. b Analysis of the relationship between expression of HOTTIP and the OS of patients with OC by Kaplan-Meier analysis. c The correlation between the expression of HOTTIP and IL-6. d The correlation between the expression of HOTTIP and PD-L1. * p < 0.05 vs. normal fallopian tube fimbriae tissues; # p < 0.05 vs. the IL-6(−/+); & p < 0.05 vs. patients with lower expression of HOTTIP. The measurement data were summarized as mean ± standard deviation. The unpaired t test was used to compare the data between two groups. The experiment was repeated 3 times independently

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