Fig. 1

The expression of circDENND4C is enhanced in breast cancer under hypoxia. a circDENND4C expression in breast cancer tissues and adjacent normal samples was measured by qRT-PCR. n = 43. b The level of circDENND4C was detected in breast cancer cells (MDA-MB-453 and SK-BR-3) and normal cells (MCF-10A) by qRT-PCR. c and d The abundance of circDENND4C was examined in MDA-MB-453 and SK-BR-3 cells after hypoxia exposure for various time by qRT-PCR. *P < 0.05, **P < 0.01, ***P < 0.001