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Table 1 Association between circDENND4C and the clinicopathological characteristics of breast cancer

From: Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia

 

N (%)

circDENND4C level

P value

High (%)

Low (%)

Age(years)

P > 0.05

  ≥ 55

24 (55.8)

13 (54.2)

11 (45.8)

 

  < 55

19 (44.2)

10 (52.6)

9 (47.4)

 

Menopause

P > 0.05

 No

26 (60.5)

14 (53.8)

12 (46.2)

 

 Yes

17 (39.5)

9 (52.9)

8 (47.1)

 

TNM stage

P < 0.05

 I-II

23 (53.5)

8 (34.8)

15 (65.2)

 

 III-IV

20 (46.5)

15 (75.0)

5 (25.0)

 

Lymph node metastasis

P < 0.05

 No

22 (51.2)

8 (36.4)

14 (63.6)

 

 Yes

21 (48.8)

15 (71.4)

6 (28.6)

 

Tumor size

P < 0.05

  ≥ 2 cm

25 (58.1)

17 (68.0)

8 (32.0)

 

  < 2 cm

18 (41.9)

6 (33.3)

12 (66.7)

 

Subtype

   

P > 0.05

 TNBC

19 (44.2)

10 (52.6)

9 (47.4)

 

 HER2

5 (11.6)

3 (60.0)

2 (40.0)

 

 Luminal A

8 (18.6)

4 (50)

4 (50)

 

 Luminal B

11 (25.6)

6 (54.5)

5 (45.5)

 
  1. Abbreviations: TNM tumor node metastasis, TNBC triple negative breast cancer, HER2 human epidermal growth factor receptor 2