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Table 1 Association between circDENND4C and the clinicopathological characteristics of breast cancer

From: Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia

  N (%) circDENND4C level P value
High (%) Low (%)
Age(years) P > 0.05
  ≥ 55 24 (55.8) 13 (54.2) 11 (45.8)  
  < 55 19 (44.2) 10 (52.6) 9 (47.4)  
Menopause P > 0.05
 No 26 (60.5) 14 (53.8) 12 (46.2)  
 Yes 17 (39.5) 9 (52.9) 8 (47.1)  
TNM stage P < 0.05
 I-II 23 (53.5) 8 (34.8) 15 (65.2)  
 III-IV 20 (46.5) 15 (75.0) 5 (25.0)  
Lymph node metastasis P < 0.05
 No 22 (51.2) 8 (36.4) 14 (63.6)  
 Yes 21 (48.8) 15 (71.4) 6 (28.6)  
Tumor size P < 0.05
  ≥ 2 cm 25 (58.1) 17 (68.0) 8 (32.0)  
  < 2 cm 18 (41.9) 6 (33.3) 12 (66.7)  
Subtype     P > 0.05
 TNBC 19 (44.2) 10 (52.6) 9 (47.4)  
 HER2 5 (11.6) 3 (60.0) 2 (40.0)  
 Luminal A 8 (18.6) 4 (50) 4 (50)  
 Luminal B 11 (25.6) 6 (54.5) 5 (45.5)  
  1. Abbreviations: TNM tumor node metastasis, TNBC triple negative breast cancer, HER2 human epidermal growth factor receptor 2