Fig. 1

Upregulation of TRIP13 in HCC. a Volcano plot indicated differentially expressed AAA ATPase genes in TCGA LIHC dataset. b Studies from GEO datasets showed higher mRNA expression of TRIP13 in HCC tissues. c-d The mRNA and protein expression of TRIP13 in 15 pairs of HCC (T) and peritumor tissues (P) were analyzed by real-time PCR and western blot. The representative images were shown. e The expression of TRIP13 was detected by IHC in a TMA including 96 HCC cases and typical photos were presented. f IHC results presented the increase of TRIP13 protein in HCC compared with peritumor samples. G Survival analysis of TRIP13 expression in 96 HCC patients. **P < 0.01