TY - JOUR AU - Redman, J. M. AU - Gibney, G. T. AU - Atkins, M. B. PY - 2016 DA - 2016// TI - Advances in immunotherapy for melanoma JO - BMC Med VL - 14 UR - https://doi.org/10.1186/s12916-016-0571-0 DO - 10.1186/s12916-016-0571-0 ID - Redman2016 ER - TY - JOUR AU - Robert, C. AU - Thomas, L. AU - Bondarenko, I. AU - O’Day, S. AU - Weber, J. AU - Garbe, C. PY - 2011 DA - 2011// TI - Ipilimumab plus dacarbazine for previously untreated metastatic melanoma JO - N Engl J Med VL - 364 UR - https://doi.org/10.1056/NEJMoa1104621 DO - 10.1056/NEJMoa1104621 ID - Robert2011 ER - TY - JOUR AU - Robert, C. AU - Long, G. V. AU - Brady, B. AU - Dutriaux, C. AU - Maio, M. AU - Mortier, L. PY - 2015 DA - 2015// TI - Nivolumab in previously untreated melanoma without BRAF mutation JO - N Engl J Med VL - 372 UR - https://doi.org/10.1056/NEJMoa1412082 DO - 10.1056/NEJMoa1412082 ID - Robert2015 ER - TY - JOUR AU - Robert, C. AU - Schachter, J. AU - Long, G. V. AU - Arance, A. AU - Grob, J. J. AU - Mortier, L. PY - 2015 DA - 2015// TI - Pembrolizumab versus Ipilimumab in advanced melanoma JO - N Engl J Med VL - 372 UR - https://doi.org/10.1056/NEJMoa1503093 DO - 10.1056/NEJMoa1503093 ID - Robert2015 ER - TY - JOUR AU - Postow, M. A. AU - Chesney, J. AU - Pavlick, A. C. AU - Robert, C. AU - Grossmann, K. AU - McDermott, D. PY - 2015 DA - 2015// TI - Nivolumab and ipilimumab versus ipilimumab in untreated melanoma JO - N Engl J Med VL - 372 UR - https://doi.org/10.1056/NEJMoa1414428 DO - 10.1056/NEJMoa1414428 ID - Postow2015 ER - TY - JOUR AU - Larkin, J. AU - Chiarion-Sileni, V. AU - Gonzalez, R. AU - Grob, J. J. AU - Cowey, C. L. AU - Lao, C. D. PY - 2015 DA - 2015// TI - Combined Nivolumab and Ipilimumab or monotherapy in untreated melanoma JO - N Engl J Med VL - 373 UR - https://doi.org/10.1056/NEJMoa1504030 DO - 10.1056/NEJMoa1504030 ID - Larkin2015 ER - TY - JOUR AU - Sharpe, A. H. AU - Wherry, E. J. AU - Ahmed, R. AU - Freeman, G. J. PY - 2007 DA - 2007// TI - The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection JO - Nat Immunol VL - 8 UR - https://doi.org/10.1038/ni1443 DO - 10.1038/ni1443 ID - Sharpe2007 ER - TY - JOUR AU - Daud, A. I. AU - Wolchok, J. D. AU - Robert, C. AU - Hwu, W. J. AU - Weber, J. S. AU - Ribas, A. PY - 2016 DA - 2016// TI - Programmed death-ligand 1 expression and response to the anti-programmed death 1 antibody Pembrolizumab in melanoma JO - J Clin Oncol VL - 34 UR - https://doi.org/10.1200/JCO.2016.67.2477 DO - 10.1200/JCO.2016.67.2477 ID - Daud2016 ER - TY - JOUR AU - Ribas, A. AU - Puzanov, I. AU - Dummer, R. AU - Schadendorf, D. AU - Hamid, O. AU - Robert, C. PY - 2015 DA - 2015// TI - Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial JO - Lancet Oncol VL - 16 UR - https://doi.org/10.1016/S1470-2045(15)00083-2 DO - 10.1016/S1470-2045(15)00083-2 ID - Ribas2015 ER - TY - JOUR AU - Weng, Y. M. AU - Peng, M. AU - Hu, M. X. AU - Yao, Y. AU - Song, Q. B. PY - 2018 DA - 2018// TI - Clinical and molecular characteristics associated with the efficacy of PD-1/PD-L1 inhibitors for solid tumors: a meta-analysis JO - Onco Targets Ther VL - 11 UR - https://doi.org/10.2147/OTT.S167865 DO - 10.2147/OTT.S167865 ID - Weng2018 ER - TY - JOUR AU - Pardoll, D. M. PY - 2012 DA - 2012// TI - The blockade of immune checkpoints in cancer immunotherapy JO - Nat Rev Cancer VL - 12 UR - https://doi.org/10.1038/nrc3239 DO - 10.1038/nrc3239 ID - Pardoll2012 ER - TY - JOUR AU - Ribas, A. PY - 2015 DA - 2015// TI - Adaptive immune resistance: how Cancer protects from immune attack JO - Cancer Discov VL - 5 UR - https://doi.org/10.1158/2159-8290.CD-15-0563 DO - 10.1158/2159-8290.CD-15-0563 ID - Ribas2015 ER - TY - JOUR AU - Tseng, S. Y. AU - Otsuji, M. AU - Gorski, K. AU - Huang, X. AU - Slansky, J. E. AU - Pai, S. I. PY - 2001 DA - 2001// TI - B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells JO - J Exp Med VL - 193 UR - https://doi.org/10.1084/jem.193.7.839 DO - 10.1084/jem.193.7.839 ID - Tseng2001 ER - TY - JOUR AU - Dong, H. AU - Strome, S. E. AU - Salomao, D. R. AU - Tamura, H. AU - Hirano, F. AU - Flies, D. B. PY - 2002 DA - 2002// TI - Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion JO - Nat Med VL - 8 UR - https://doi.org/10.1038/nm730 DO - 10.1038/nm730 ID - Dong2002 ER - TY - JOUR AU - Wang, L. AU - Pino-Lagos, K. AU - Vries, V. C. AU - Guleria, I. AU - Sayegh, M. H. AU - Noelle, R. J. PY - 2008 DA - 2008// TI - Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells JO - Proc Natl Acad Sci U S A VL - 105 UR - https://doi.org/10.1073/pnas.0710441105 DO - 10.1073/pnas.0710441105 ID - Wang2008 ER - TY - JOUR AU - Sun, C. AU - Mezzadra, R. AU - Schumacher, T. N. PY - 2018 DA - 2018// TI - Regulation and function of the PD-L1 checkpoint JO - Immunity VL - 48 UR - https://doi.org/10.1016/j.immuni.2018.03.014 DO - 10.1016/j.immuni.2018.03.014 ID - Sun2018 ER - TY - JOUR AU - Atefi, M. AU - Avramis, E. AU - Lassen, A. AU - Wong, D. J. AU - Robert, L. AU - Foulad, D. PY - 2014 DA - 2014// TI - Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma JO - Clin Cancer Res VL - 20 UR - https://doi.org/10.1158/1078-0432.CCR-13-2797 DO - 10.1158/1078-0432.CCR-13-2797 ID - Atefi2014 ER - TY - JOUR AU - Garcia-Diaz, A. AU - Shin, D. S. AU - Moreno, B. H. AU - Saco, J. AU - Escuin-Ordinas, H. AU - Rodriguez, G. A. PY - 2017 DA - 2017// TI - Interferon receptor signaling pathways regulating PD-L1 and PD-L2 expression JO - Cell Rep VL - 19 UR - https://doi.org/10.1016/j.celrep.2017.04.031 DO - 10.1016/j.celrep.2017.04.031 ID - Garcia-Diaz2017 ER - TY - JOUR AU - Schroder, K. AU - Hertzog, P. J. AU - Ravasi, T. AU - Hume, D. A. PY - 2004 DA - 2004// TI - Interferon-gamma: an overview of signals, mechanisms and functions JO - J Leukoc Biol VL - 75 UR - https://doi.org/10.1189/jlb.0603252 DO - 10.1189/jlb.0603252 ID - Schroder2004 ER - TY - JOUR AU - Audrito, V. AU - Serra, S. AU - Stingi, A. AU - Orso, F. AU - Gaudino, F. AU - Bologna, C. PY - 2017 DA - 2017// TI - PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p JO - Oncotarget VL - 8 UR - https://doi.org/10.18632/oncotarget.15213 DO - 10.18632/oncotarget.15213 ID - Audrito2017 ER - TY - JOUR AU - Chen, L. AU - Gibbons, D. L. AU - Goswami, S. AU - Cortez, M. A. AU - Ahn, Y. H. AU - Byers, L. A. PY - 2014 DA - 2014// TI - Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression JO - Nat Commun VL - 5 UR - https://doi.org/10.1038/ncomms6241 DO - 10.1038/ncomms6241 ID - Chen2014 ER - TY - JOUR AU - Fujita, Y. AU - Yagishita, S. AU - Hagiwara, K. AU - Yoshioka, Y. AU - Kosaka, N. AU - Takeshita, F. PY - 2015 DA - 2015// TI - The clinical relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancer JO - Mol Ther VL - 23 UR - https://doi.org/10.1038/mt.2015.10 DO - 10.1038/mt.2015.10 ID - Fujita2015 ER - TY - JOUR AU - Gong, A. Y. AU - Zhou, R. AU - Hu, G. AU - Li, X. AU - Splinter, P. L. AU - O’Hara, S. P. PY - 2009 DA - 2009// TI - MicroRNA-513 regulates B7-H1 translation and is involved in IFN-gamma-induced B7-H1 expression in cholangiocytes JO - J Immunol VL - 182 UR - https://doi.org/10.4049/jimmunol.182.3.1325 DO - 10.4049/jimmunol.182.3.1325 ID - Gong2009 ER - TY - JOUR AU - Wang, W. AU - Sun, J. AU - Li, F. AU - Li, R. AU - Gu, Y. AU - Liu, C. PY - 2012 DA - 2012// TI - A frequent somatic mutation in CD274 3′-UTR leads to protein over-expression in gastric cancer by disrupting miR-570 binding JO - Hum Mutat VL - 33 UR - https://doi.org/10.1002/humu.22014 DO - 10.1002/humu.22014 ID - Wang2012 ER - TY - JOUR AU - Xu, S. AU - Tao, Z. AU - Hai, B. AU - Liang, H. AU - Shi, Y. AU - Wang, T. PY - 2016 DA - 2016// TI - miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpoint JO - Nat Commun VL - 7 UR - https://doi.org/10.1038/ncomms11406 DO - 10.1038/ncomms11406 ID - Xu2016 ER - TY - JOUR AU - Zhao, L. AU - Yu, H. AU - Yi, S. AU - Peng, X. AU - Su, P. AU - Xiao, Z. PY - 2016 DA - 2016// TI - The tumor suppressor miR-138-5p targets PD-L1 in colorectal cancer JO - Oncotarget VL - 7 ID - Zhao2016 ER - TY - JOUR AU - Cortez, M. A. AU - Ivan, C. AU - Valdecanas, D. AU - Wang, X. AU - Peltier, H. J. AU - Ye, Y. PY - 2016 DA - 2016// TI - PDL1 regulation by p53 via miR-34 JO - J Natl Cancer Inst VL - 108 UR - https://doi.org/10.1093/jnci/djv303 DO - 10.1093/jnci/djv303 ID - Cortez2016 ER - TY - JOUR AU - Kim, M. P. AU - Lozano, G. PY - 2018 DA - 2018// TI - Mutant p53 partners in crime JO - Cell Death Differ VL - 25 UR - https://doi.org/10.1038/cdd.2017.185 DO - 10.1038/cdd.2017.185 ID - Kim2018 ER - TY - JOUR AU - Kastenhuber, E. R. AU - Lowe, S. W. PY - 2017 DA - 2017// TI - Putting p53 in context JO - Cell VL - 170 UR - https://doi.org/10.1016/j.cell.2017.08.028 DO - 10.1016/j.cell.2017.08.028 ID - Kastenhuber2017 ER - TY - JOUR AU - Vieler, M. AU - Sanyal, S. PY - 2018 DA - 2018// TI - p53 Isoforms and Their Implications in Cancer JO - Cancers (Basel) VL - 10 UR - https://doi.org/10.3390/cancers10090288 DO - 10.3390/cancers10090288 ID - Vieler2018 ER - TY - JOUR AU - Herold, M. J. AU - Brandt, J. AU - Seibler, J. AU - Reichardt, H. M. PY - 2008 DA - 2008// TI - Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats JO - Proc Natl Acad Sci U S A VL - 105 UR - https://doi.org/10.1073/pnas.0806213105 DO - 10.1073/pnas.0806213105 ID - Herold2008 ER - TY - JOUR AU - Houben, R. AU - Adam, C. AU - Baeurle, A. AU - Hesbacher, S. AU - Grimm, J. AU - Angermeyer, S. PY - 2012 DA - 2012// TI - An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells JO - Int J Cancer VL - 130 UR - https://doi.org/10.1002/ijc.26076 DO - 10.1002/ijc.26076 ID - Houben2012 ER - TY - JOUR AU - Houben, R. AU - Hesbacher, S. AU - Schmid, C. P. AU - Kauczok, C. S. AU - Flohr, U. AU - Haferkamp, S. PY - 2011 DA - 2011// TI - High-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assays JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0022096 DO - 10.1371/journal.pone.0022096 ID - Houben2011 ER - TY - JOUR AU - Lin, J. AU - Chen, J. AU - Elenbaas, B. AU - Levine, A. J. PY - 1994 DA - 1994// TI - Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein JO - Genes Dev VL - 8 UR - https://doi.org/10.1101/gad.8.10.1235 DO - 10.1101/gad.8.10.1235 ID - Lin1994 ER - TY - JOUR AU - Appenzeller, S. AU - Gesierich, A. AU - Thiem, A. AU - Hufnagel, A. AU - Jessen, C. AU - Kneitz, H. PY - 2019 DA - 2019// TI - The identification of patient-specific mutations reveals dual pathway activation in most patients with melanoma and activated receptor tyrosine kinases in BRAF/NRAS wild-type melanomas JO - Cancer VL - 125 UR - https://doi.org/10.1002/cncr.31843 DO - 10.1002/cncr.31843 ID - Appenzeller2019 ER - TY - BOOK PY - 2008 DA - 2008// TI - R: A language and environment for statistical computing PB - R Foundation for Statistical Computing CY - Vienna ID - ref36 ER - TY - JOUR AU - Colaprico, A. AU - Silva, T. C. AU - Olsen, C. AU - Garofano, L. AU - Cava, C. AU - Garolini, D. PY - 2016 DA - 2016// TI - TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data JO - Nucleic Acids Res VL - 44 UR - https://doi.org/10.1093/nar/gkv1507 DO - 10.1093/nar/gkv1507 ID - Colaprico2016 ER - TY - STD TI - Mayakonda A, Koeffler HP. Maftools: Efficient analysis, visualization and summarization of MAF files from large-scale cohort based cancer studies: bioRxiv. 2016. https://www.biorxiv.org/content/10.1101/052662v1.article-info. UR - https://www.biorxiv.org/content/10.1101/052662v1.article-info ID - ref38 ER - TY - JOUR AU - Li, J. AU - Lu, Y. AU - Akbani, R. AU - Ju, Z. AU - Roebuck, P. L. AU - Liu, W. PY - 2013 DA - 2013// TI - TCPA: a resource for cancer functional proteomics data JO - Nat Methods VL - 10 UR - https://doi.org/10.1038/nmeth.2650 DO - 10.1038/nmeth.2650 ID - Li2013 ER - TY - JOUR AU - Robinson, M. D. AU - McCarthy, D. J. AU - Smyth, G. K. PY - 2010 DA - 2010// TI - edgeR: a Bioconductor package for differential expression analysis of digital gene expression data JO - Bioinformatics VL - 26 UR - https://doi.org/10.1093/bioinformatics/btp616 DO - 10.1093/bioinformatics/btp616 ID - Robinson2010 ER - TY - JOUR AU - Ritter, C. AU - Fan, K. AU - Paschen, A. AU - Reker Hardrup, S. AU - Ferrone, S. AU - Nghiem, P. PY - 2017 DA - 2017// TI - Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/s41598-017-02608-0 DO - 10.1038/s41598-017-02608-0 ID - Ritter2017 ER - TY - JOUR AU - Schmittgen, T. D. AU - Livak, K. J. PY - 2008 DA - 2008// TI - Analyzing real-time PCR data by the comparative C(T) method JO - Nat Protoc VL - 3 UR - https://doi.org/10.1038/nprot.2008.73 DO - 10.1038/nprot.2008.73 ID - Schmittgen2008 ER - TY - BOOK AU - Wickham, H. PY - 2009 DA - 2009// TI - ggplot2: Elegant Graphics for Data Analysis PB - Springer-Verlag CY - New York UR - https://doi.org/10.1007/978-0-387-98141-3 DO - 10.1007/978-0-387-98141-3 ID - Wickham2009 ER - TY - JOUR AU - Gu, Z. AU - Eils, R. AU - Schlesner, M. PY - 2016 DA - 2016// TI - Complex heatmaps reveal patterns and correlations in multidimensional genomic data JO - Bioinformatics VL - 32 UR - https://doi.org/10.1093/bioinformatics/btw313 DO - 10.1093/bioinformatics/btw313 ID - Gu2016 ER - TY - JOUR AU - Mi, H. AU - Huang, X. AU - Muruganujan, A. AU - Tang, H. AU - Mills, C. AU - Kang, D. PY - 2017 DA - 2017// TI - PANTHER version 11: expanded annotation data from gene ontology and Reactome pathways, and data analysis tool enhancements JO - Nucleic Acids Res VL - 45 UR - https://doi.org/10.1093/nar/gkw1138 DO - 10.1093/nar/gkw1138 ID - Mi2017 ER - TY - JOUR AU - Mi, H. AU - Thomas, P. PY - 2009 DA - 2009// TI - PANTHER pathway: an ontology-based pathway database coupled with data analysis tools JO - Methods Mol Biol VL - 563 UR - https://doi.org/10.1007/978-1-60761-175-2_7 DO - 10.1007/978-1-60761-175-2_7 ID - Mi2009 ER - TY - JOUR AU - Fischer, M. PY - 2017 DA - 2017// TI - Census and evaluation of p53 target genes JO - Oncogene VL - 36 UR - https://doi.org/10.1038/onc.2016.502 DO - 10.1038/onc.2016.502 ID - Fischer2017 ER - TY - JOUR AU - Youlyouz-Marfak, I. AU - Gachard, N. AU - Clorennec, C. AU - Najjar, I. AU - Baran-Marszak, F. AU - Reminieras, L. PY - 2008 DA - 2008// TI - Identification of a novel p53-dependent activation pathway of STAT1 by antitumour genotoxic agents JO - Cell Death Differ VL - 15 UR - https://doi.org/10.1038/sj.cdd.4402270 DO - 10.1038/sj.cdd.4402270 ID - Youlyouz-Marfak2008 ER - TY - JOUR AU - Decker, T. AU - Kovarik, P. PY - 2000 DA - 2000// TI - Serine phosphorylation of STATs JO - Oncogene VL - 19 UR - https://doi.org/10.1038/sj.onc.1203481 DO - 10.1038/sj.onc.1203481 ID - Decker2000 ER - TY - JOUR AU - Tanikawa, C. AU - Zhang, Y. Z. AU - Yamamoto, R. AU - Tsuda, Y. AU - Tanaka, M. AU - Funauchi, Y. PY - 2017 DA - 2017// TI - The transcriptional landscape of p53 Signalling pathway JO - EBioMedicine VL - 20 UR - https://doi.org/10.1016/j.ebiom.2017.05.017 DO - 10.1016/j.ebiom.2017.05.017 ID - Tanikawa2017 ER - TY - JOUR AU - Box, N. F. AU - Vukmer, T. O. AU - Terzian, T. PY - 2014 DA - 2014// TI - Targeting p53 in melanoma JO - Pigment Cell Melanoma Res VL - 27 UR - https://doi.org/10.1111/pcmr.12180 DO - 10.1111/pcmr.12180 ID - Box2014 ER - TY - JOUR AU - Munoz-Fontela, C. AU - Mandinova, A. AU - Aaronson, S. A. AU - Lee, S. W. PY - 2016 DA - 2016// TI - Emerging roles of p53 and other tumour-suppressor genes in immune regulation JO - Nat Rev Immunol VL - 16 UR - https://doi.org/10.1038/nri.2016.99 DO - 10.1038/nri.2016.99 ID - Munoz-Fontela2016 ER - TY - JOUR AU - Braun, M. W. AU - Iwakuma, T. PY - 2016 DA - 2016// TI - Regulation of cytotoxic T-cell responses by p53 in cancer JO - Transl Cancer Res VL - 5 UR - https://doi.org/10.21037/tcr.2016.11.76 DO - 10.21037/tcr.2016.11.76 ID - Braun2016 ER - TY - JOUR AU - Zhu, K. AU - Wang, J. AU - Zhu, J. AU - Jiang, J. AU - Shou, J. AU - Chen, X. PY - 1999 DA - 1999// TI - p53 induces TAP1 and enhances the transport of MHC class I peptides JO - Oncogene VL - 18 UR - https://doi.org/10.1038/sj.onc.1203235 DO - 10.1038/sj.onc.1203235 ID - Zhu1999 ER - TY - JOUR AU - Wang, B. AU - Niu, D. AU - Lai, L. AU - Ren, E. C. PY - 2013 DA - 2013// TI - p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1 JO - Nat Commun VL - 4 UR - https://doi.org/10.1038/ncomms3359 DO - 10.1038/ncomms3359 ID - Wang2013 ER - TY - JOUR AU - Xiao, W. AU - Du, N. AU - Huang, T. AU - Guo, J. AU - Mo, X. AU - Yuan, T. PY - 2018 DA - 2018// TI - TP53 mutation as potential negative predictor for response of anti-CTLA-4 therapy in metastatic melanoma JO - EBioMedicine VL - 32 UR - https://doi.org/10.1016/j.ebiom.2018.05.019 DO - 10.1016/j.ebiom.2018.05.019 ID - Xiao2018 ER - TY - JOUR AU - DeLeon, T. AU - Kipp, B. AU - Langlais, B. AU - Flotte, T. AU - Winters, J. AU - Kosiorek, H. E. PY - 2017 DA - 2017// TI - Assessment of treatment response to immunotherapy in melanoma patients with pathogenic mutations of NRAS, BRAF, CDKN2A and P53 JO - J Clin Oncol VL - 35 UR - https://doi.org/10.1200/JCO.2017.35.15_suppl.e21057 DO - 10.1200/JCO.2017.35.15_suppl.e21057 ID - DeLeon2017 ER - TY - JOUR AU - Yu, X. Y. AU - Zhang, X. W. AU - Wang, F. AU - Lin, Y. B. AU - Wang, W. D. AU - Chen, Y. Q. PY - 2018 DA - 2018// TI - Correlation and prognostic significance of PD-L1 and P53 expression in resected primary pulmonary lymphoepithelioma-like carcinoma JO - J Thorac Dis VL - 10 UR - https://doi.org/10.21037/jtd.2018.03.14 DO - 10.21037/jtd.2018.03.14 ID - Yu2018 ER - TY - JOUR AU - Agersborg, S. AU - Jiang, S. AU - Chen, W. AU - Ma, W. AU - Albitar, M. PY - 2016 DA - 2016// TI - PD-L1 expression correlation with TP53 gene mutation status in lung cancer but not in colorectal cancer JO - J Clin Oncol VL - 34 UR - https://doi.org/10.1200/JCO.2016.34.15_suppl.11557 DO - 10.1200/JCO.2016.34.15_suppl.11557 ID - Agersborg2016 ER - TY - JOUR AU - Taube, J. M. AU - Anders, R. A. AU - Young, G. D. AU - Xu, H. AU - Sharma, R. AU - McMiller, T. L. PY - 2012 DA - 2012// TI - Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape JO - Sci Transl Med VL - 4 UR - https://doi.org/10.1126/scitranslmed.3003689 DO - 10.1126/scitranslmed.3003689 ID - Taube2012 ER - TY - JOUR AU - Tumeh, P. C. AU - Harview, C. L. AU - Yearley, J. H. AU - Shintaku, I. P. AU - Taylor, E. J. AU - Robert, L. PY - 2014 DA - 2014// TI - PD-1 blockade induces responses by inhibiting adaptive immune resistance JO - Nature VL - 515 UR - https://doi.org/10.1038/nature13954 DO - 10.1038/nature13954 ID - Tumeh2014 ER - TY - JOUR AU - Knol, A. C. AU - Nguyen, J. M. AU - Pandolfino, M. C. AU - Denis, M. G. AU - Khammari, A. AU - Dreno, B. PY - 2018 DA - 2018// TI - PD-L1 expression by tumor cell lines: a predictive marker in melanoma JO - Exp Dermatol VL - 27 UR - https://doi.org/10.1111/exd.13526 DO - 10.1111/exd.13526 ID - Knol2018 ER - TY - JOUR AU - Wiesner, T. AU - Kiuru, M. AU - Scott, S. N. AU - Arcila, M. AU - Halpern, A. C. AU - Hollmann, T. PY - 2015 DA - 2015// TI - NF1 mutations are common in desmoplastic melanoma JO - Am J Surg Pathol VL - 39 UR - https://doi.org/10.1097/PAS.0000000000000451 DO - 10.1097/PAS.0000000000000451 ID - Wiesner2015 ER - TY - JOUR AU - Kraft, S. AU - Fernandez-Figueras, M. T. AU - Richarz, N. A. AU - Flaherty, K. T. AU - Hoang, M. P. PY - 2017 DA - 2017// TI - PDL1 expression in desmoplastic melanoma is associated with tumor aggressiveness and progression JO - J Am Acad Dermatol VL - 77 UR - https://doi.org/10.1016/j.jaad.2017.05.007 DO - 10.1016/j.jaad.2017.05.007 ID - Kraft2017 ER - TY - JOUR AU - Speidel, D. PY - 2010 DA - 2010// TI - Transcription-independent p53 apoptosis: an alternative route to death JO - Trends Cell Biol VL - 20 UR - https://doi.org/10.1016/j.tcb.2009.10.002 DO - 10.1016/j.tcb.2009.10.002 ID - Speidel2010 ER - TY - JOUR AU - Speidel, D. AU - Helmbold, H. AU - Deppert, W. PY - 2006 DA - 2006// TI - Dissection of transcriptional and non-transcriptional p53 activities in the response to genotoxic stress JO - Oncogene VL - 25 UR - https://doi.org/10.1038/sj.onc.1209126 DO - 10.1038/sj.onc.1209126 ID - Speidel2006 ER - TY - JOUR AU - Yoon, K. W. AU - Byun, S. AU - Kwon, E. AU - Hwang, S. Y. AU - Chu, K. AU - Hiraki, M. PY - 2015 DA - 2015// TI - Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53 JO - Science VL - 349 UR - https://doi.org/10.1126/science.1261669 DO - 10.1126/science.1261669 ID - Yoon2015 ER - TY - JOUR AU - Gowrishankar, K. AU - Gunatilake, D. AU - Gallagher, S. J. AU - Tiffen, J. AU - Rizos, H. AU - Hersey, P. PY - 2015 DA - 2015// TI - Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-kappaB JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0123410 DO - 10.1371/journal.pone.0123410 ID - Gowrishankar2015 ER - TY - JOUR AU - Lowe, J. M. AU - Menendez, D. AU - Bushel, P. R. AU - Shatz, M. AU - Kirk, E. L. AU - Troester, M. A. PY - 2014 DA - 2014// TI - p53 and NF-kappaB coregulate proinflammatory gene responses in human macrophages JO - Cancer Res VL - 74 UR - https://doi.org/10.1158/0008-5472.CAN-13-1070 DO - 10.1158/0008-5472.CAN-13-1070 ID - Lowe2014 ER - TY - JOUR AU - Luo, N. AU - Formisano, L. AU - Gonzalez-Ericsson, P. I. AU - Sanchez, V. AU - Dean, P. T. AU - Opalenik, S. R. PY - 2018 DA - 2018// TI - Melanoma response to anti-PD-L1 immunotherapy requires JAK1 signaling, but not JAK2 JO - Oncoimmunology VL - 7 UR - https://doi.org/10.1080/2162402X.2018.1438106 DO - 10.1080/2162402X.2018.1438106 ID - Luo2018 ER - TY - JOUR AU - Shin, D. S. AU - Zaretsky, J. M. AU - Escuin-Ordinas, H. AU - Garcia-Diaz, A. AU - Hu-Lieskovan, S. AU - Kalbasi, A. PY - 2017 DA - 2017// TI - Primary resistance to PD-1 blockade mediated by JAK1/2 mutations JO - Cancer Discov VL - 7 UR - https://doi.org/10.1158/2159-8290.CD-16-1223 DO - 10.1158/2159-8290.CD-16-1223 ID - Shin2017 ER - TY - JOUR AU - Zaretsky, J. M. AU - Garcia-Diaz, A. AU - Shin, D. S. AU - Escuin-Ordinas, H. AU - Hugo, W. AU - Hu-Lieskovan, S. PY - 2016 DA - 2016// TI - Mutations associated with acquired resistance to PD-1 blockade in melanoma JO - N Engl J Med VL - 375 UR - https://doi.org/10.1056/NEJMoa1604958 DO - 10.1056/NEJMoa1604958 ID - Zaretsky2016 ER -