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Table 1 Relevance of Analysis of METTL3 Expression in CRC Patients

From: Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway

METTL3 Level

Characteristics

n

Low

High

X 2

P

Age (years)

  < 60

19

10

09

0.075

0.786

  > 60

41

20

21

Gender

 Male

33

14

19

1.674

0.201

 Female

27

16

11

Lymph node metastasis

 Negative

28

19

09

7.286

0.009**

 Positive

32

11

21

Distant metastasis

 Negative

40

24

16

5.043

0.029*

 Positive

20

06

14

Tumor stage

 Stage 1,2

24

15

09

2.552

0.118

 Stage 3,4

36

15

21

TNM staging system

 T1 + T2

29

18

11

3.344

0.073

 T3 + T4

31

12

19

Tumor size (cm)

  > 5

26

12

14

0.264

0.610

  < 5

34

18

16

  1. NOTE: A chi-square test was used for comparing groups between low and high METTL3 expression. *P < 0.05, **P < 0.01