Fig. 1
The expression and prognostic value of UFM1 in gastric cancer. a The mRNA levels of UFM1 in gastric tumors and respective adjacent tissues were measured by real-time qPCR. The ratios of UFM1 in gastric tumor compared to respective tissues (T/N) from 116 patients are presented. b The protein levels of UFM1 in gastric tumor tissues and respective adjacent tissues from 140 patients were measured using western blotting. The representative results are shown. c The T/N ratios of the total results described in (b). d The expression of UFM1 protein in gastric tumor tissues and respective adjacent tissues were analyzed using IHC (Representative results are shown, magnification, × 100 and × 400). e UFM1 expression scores are shown as box plots, with the horizontal lines representing the median; the bottom and top of the boxes representing the 25th and 75th percentiles, respectively; and the vertical bars representing the range of data. The expression of UFM1 in gastric tumor tissues and respective adjacent tissues was compared using the t-test. n = 120 (*, P < 0.005). f Kaplan Meier survival curve of gastric cancer patients with “High UFM1” or “Low UFM1” (P < 0.05, log-rank test). g Endogenous expression of UFM1 in various human gastric cancer cell lines by western blot