Fig. 6

Effect of UFM1 and PDK1 on prognosis of patients with gastric cancer. a The expression of PDK1 protein in gastric tumor tissues and respective adjacent tissues were analyzed using IHC, magnification, × 100 and × 400. b PDK1 expression scores are shown as box plots. The expression of PDK1 in gastric tumor tissues and respective adjacent tissues was compared using the t-test. n = 120 (*, P < 0.005). c Kaplan-Meier survival curve of gastric cancer patients with “High PDK1” or “Low PDK1” (P < 0.05, log-rank test). d Kaplan-Meier analysis of the correlation between the combined expression of UFM1 and PDK1 with the overall survival of gastric cancer patients (P < 0.05, log-rank test). e Working model of the role of UFM1 in PDK1 signaling and gastric cancer cell invasion