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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular carcinoma

Fig. 5

Inhibition of PI3K/AKT pathway contributes to the radiosensitization effect upon HCC cells. Under irradiation exposure, the effect of LY294002 (a) and MK2206 (b) on SMMC-7721 and MHCC97H cell apoptosis was assessed quantitatively by Annexin V-PI staining assays, respectively. c-d Protein expression of important genes in PI3K/AKT signaling and γ-H2AX were detected by Western blot at 24 h after IR

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