Patient | Date of sample (m/y) | Stage | Large T-ag | %TrkA Mean (SD) | %TrkAIII Mean (SD) | Mean (SD) Ratio TrkA:18S rRNA | Mean (SD) Ratio TrkAIII:18S rRNA | IF anti-TrkA | IF anti-pY490 TrkA | Therapy |
---|---|---|---|---|---|---|---|---|---|---|
MCC | ||||||||||
 1 | 06–2014 (i) | IV | H | 1.88 (4.5) | 98.12 (4.5) | 0.016 (0.002) | 0.834 (0.03) | S | S | S/C |
09–2014 (ii) | IV | H | 23.4 (8.4) | 76.6 (8.4) | 0.036 (0.007) | 0.12 (0.01 | M | M | S/C | |
12–2014 (iii) | IV | M/H | 23.1 (6.5) | 76.9 (6.5) | 0.08 (0.001) | 0.44 (0.02) | S | M | S/C | |
08–2015 (iv) | IV | H | 8.6 (5.4) | 91.4 (5.4) | 0.034 (0.001) | 0.4 (0.01) | M | M | S/C | |
 2 | 02–2008 (i) | IV | H | 31.9 (4.5) | 68.1 (4.5) | 0.2 (0.01) | 0.43 (0.02) | S | S | S/C |
02–2008 (ii) | IV | H | 1.3 (4.2) | 98.7 (4.2 | 0.003 (0.0001) | 0.26 (0.02) | S | S | S/C | |
02–2008 (iii) | IV | H | 1.9 (6.1) | 98.1 (6.1) | 0.002 (0.0001) | 0.2 (0.01) | M | S | S/C | |
 3 | 08–2011 (i) | IV | M | 0.4 (4.2) | 99.6 (4.2) | 0.003 (0.0002) | 0.68 (0.03) | S | S | S/C |
08–2011 (ii) | IV | M/H | 0.8 (8.4) | 99.2 (8.4) | 0.001 (0.0003) | 0.09 (0.002) | M | W | S/C | |
 4 | 10–2012 (i) | I | M/H | 6.2 (8.4) | 93.8 (8.4) | 0.02 (0.0013) | 0.75 (0.02) | S | S | S |
02–2013 (ii) | IV | M | 12.4 (8.2) | 87.6 (8.2) | 0.002 (0.0001) | 0.08 (0.002) | M | M | S | |
 5 | 02–2017 | IIA | H | 16.8 (7.9) | 83.2 (7.9) | 0.14 (0.005) | 0.72 (0.002) | S | W | S |
 6 | 09–2006 | IIA | H | 2.7 (8.4) | 97.3 (8.4) | 0.003 (0.0002) | 0.09 (0.003) | L | N | S |
 7 | 01–2010 | IIA | L/M | 28.5 (6.8) | 71.5 (6.8) | 0.08 (0.002) | 0.19 (0.003) | L | M | S |
 8 | 11–2007 | IIB | M/H | 58.5 (6.7) | 41.5 (6.7) | 0.2 (0.002) | 0.18 (0.003) | S | M | S |
 9 | 01–2013 | IIA | H | 47.4 (6.5) | 52.6 (6.5) | 0.19 (0.003) | 0.22 (0.004) | S | S | S |
 10 | 01–2006 | IIIB | H | 58.5 (6.7) | 41.5 (6.7) | 0.055 (0.001) | 0.08 (0.003) | L | N | S |
 11 | 01–2019 | I | N | 98.6 (0.2) | 1.4 (0.2) | 0.4 (0.002) | 0.008 (0.001) | L | N | S |
BCC | ||||||||||
 12 | 01–2018 | I | N | 99.5 (0.04) | 0.5 (0.04) | 0.1 (0.02) | 0.004 (0.0001) | N | N | S |
 13 | 02–2018 | I | N | 99.8 (0.02) | 0.2 (0.02) | 0.04 (0.002) | 0.08 (0.002) | W | N | S |
 14 | 01–2019 | I | L | 99.9 (0.04) | 0.1 (0.04) | 0.213 (0.012) | 0.02 (0.001) | N | N | S |
SCC | ||||||||||
15 | 02–2019 | I | N | 99.8 (0.02) | 0.2 (0.02) | 0.18 (0.002) | 0.001 (0.0002) | N | N | S |
16 | 01–2019 | I | N | 99.8 (0.05) | 0.2 (0.05) | 1.3 (0.03) | 0.004 (0.0002) | S | N | S |
17 | 03–2019 | I | N | 99.04 (0.05) | 0.06 (0.05) | 0.17 (0.02) | 0.008 (0.0002) | W | N | S |
Normal Skin | ||||||||||
NS 1 | Â | Â | N | 99.6 (0.02) | 0.4 (0.02) | 0.45 (0.01) | 0.0001 (0.00002) | S | N | S |
NS 2 | Â | Â | N | 99.3 (0.01) | 0.7 (0.01) | 0.66 (0.023) | 0.0001 (0.00002) | S | N | S |