Skip to main content
Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Long non-coding RNA RP11-468E2.5 curtails colorectal cancer cell proliferation and stimulates apoptosis via the JAK/STAT signaling pathway by targeting STAT5 and STAT6

Fig. 5

Effect of RP11-468E2.5 on the mRNA expression of JAK/STAT signaling pathway- and apoptosis-related genes in HCT116 and SW480 cells. a RP11-468E2.5 expression and mRNA expression of the JAK/STAT signaling pathway-related genes and apoptosis-related genes determined by RT-qPCR in HCT116 cells. b RP11-468E2.5 expression and mRNA expression of the JAK/STAT signaling pathway- and apoptosis-related genes determined by RT-qPCR in SW480 cells; RT-qPCR, reverse transcription quantitative polymerase chain reaction; NC, negative control; JAK1, janus kinase 1; STAT3, signal transducer and activator of transcription-3; STAT5, signal transducer and activator of transcription-5; STAT6, signal transducer and activator of transcription-6; Bcl-2, B-cell leukemia/lymphoma 2; CCND1, Cyclin D1. * p < 0.05, compared with the blank group

Back to article page