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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Forkhead box (FOX) G1 promotes hepatocellular carcinoma epithelial-Mesenchymal transition by activating Wnt signal through forming T-cell factor-4/Beta-catenin/FOXG1 complex

Fig. 3

FOXG1 enhances metastasis of HCC cell lines in vivo. a Representative bright-field image of the lungs. On day 35, mice that received Huh7/vector or Huh7/FOXG1 cells were anesthetized and sacrificed, and the lungs were collected. Arrows indicate surface metastatic nodules. b Number of visible surface metastatic lesions in mice (n = 5 per group) that received tail vein injection of Huh7/vector or Huh7/FOXG1 cells. c Body weight of BALB/C mice that received transplants of Huh7/vector or Huh7/FOXG1 cells. d Lung metastases in mice implanted with Huh7/vector or Huh7/FOXG1 cells were confirmed by hematoxylin and eosin (H&E) staining

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