Fig. 8

FOXG1 expression correlates with Wnt/β-catenin pathway activation in human HCC. a Tissue microarray of IHC showing that TCF4 and β-catenin expression levels were associated with FOXG1 expression in the 105 primary human HCC specimens with or without metastasis. Two representative cases are shown. b Percentages of the 105 primary human HCC specimens showing low or high TCF4 and β-catenin protein expression detected by IHC, relative to low/high FOXG1 expression. c Correlation analysis of FOXG1 expression with TCF4 (left) and β-catenin (right) expression in 105 HCC samples. Some points represent more than one specimen