TY - JOUR AU - Weller, M. AU - Bent, M. AU - Hopkins, K. AU - Tonn, J. C. AU - Stupp, R. AU - Falini, A. PY - 2014 DA - 2014// TI - EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma JO - Lancet Oncol VL - 15 UR - https://doi.org/10.1016/S1470-2045(14)70011-7 DO - 10.1016/S1470-2045(14)70011-7 ID - Weller2014 ER - TY - JOUR AU - Marcon, F. AU - Boei, J. J. AU - Natarajan, A. T. PY - 2000 DA - 2000// TI - Recombination between homologous chromosomes does not play a dominant role in the formation of radiation-induced chromosomal aberrations JO - Int J Radiat Biol. VL - 76 UR - https://doi.org/10.1080/09553000050151619 DO - 10.1080/09553000050151619 ID - Marcon2000 ER - TY - JOUR AU - Lin, Y. AU - Lukacsovich, T. AU - Waldman, A. S. PY - 1999 DA - 1999// TI - Multiple pathways for repair of DNA double-strand breaks in mammalian chromosomes JO - Mol Cell Biol VL - 19 UR - https://doi.org/10.1128/MCB.19.12.8353 DO - 10.1128/MCB.19.12.8353 ID - Lin1999 ER - TY - JOUR AU - Kastan, M. B. AU - Kuerbitz, S. J. PY - 1993 DA - 1993// TI - Control of G1 arrest after DNA damage JO - Environ Health Perspect VL - 101 UR - https://doi.org/10.1289/ehp.93101s555 DO - 10.1289/ehp.93101s555 ID - Kastan1993 ER - TY - JOUR AU - Perry, M. E. AU - Levine, A. J. PY - 1993 DA - 1993// TI - Tumor-suppressor p53 and the cell cycle JO - Curr Opin Genet Dev VL - 3 UR - https://doi.org/10.1016/S0959-437X(05)80340-5 DO - 10.1016/S0959-437X(05)80340-5 ID - Perry1993 ER - TY - JOUR AU - Ohgaki, H. PY - 2005 DA - 2005// TI - Genetic pathways to glioblastomas JO - Neuropathology. VL - 25 UR - https://doi.org/10.1111/j.1440-1789.2004.00600.x DO - 10.1111/j.1440-1789.2004.00600.x ID - Ohgaki2005 ER - TY - JOUR AU - Zhang, Y. i. n. g. AU - Dube, C. o. l. l. i. n. AU - Gibert, M. y. r. o. n. AU - Cruickshanks, N. i. c. h. o. l. a. AU - Wang, B. a. o. m. i. n. AU - Coughlan, M. a. e. v. e. AU - Yang, Y. a. n. z. h. i. AU - Setiady, I. n. i. t. h. a. AU - Deveau, C. i. a. n. a. AU - Saoud, K. a. r. i. m. AU - Grello, C. a. s. s. a. n. d. r. a. AU - Oxford, M. a. d. i. s. o. n. AU - Yuan, F. a. n. g. AU - Abounader, R. o. g. e. r. PY - 2018 DA - 2018// TI - The p53 Pathway in Glioblastoma JO - Cancers VL - 10 UR - https://doi.org/10.3390/cancers10090297 DO - 10.3390/cancers10090297 ID - Zhang2018 ER - TY - JOUR AU - Wang, X. AU - Chen, J. X. AU - Liu, J. P. AU - You, C. AU - Liu, Y. H. AU - Mao, Q. PY - 2014 DA - 2014// TI - Gain of function of mutant TP53 in glioblastoma: prognosis and response to temozolomide JO - Ann Surg Oncol. VL - 21 UR - https://doi.org/10.1245/s10434-013-3380-0 DO - 10.1245/s10434-013-3380-0 ID - Wang2014 ER - TY - JOUR AU - Moureau, S. y. l. v. i. e. AU - Luessing, J. a. n. n. a. AU - Harte, E. m. m. a. C. h. r. i. s. t. i. n. a. AU - Voisin, M. u. r. i. e. l. AU - Lowndes, N. o. e. l. F. r. a. n. c. i. s. PY - 2016 DA - 2016// TI - A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining JO - Open Biology VL - 6 UR - https://doi.org/10.1098/rsob.160225 DO - 10.1098/rsob.160225 ID - Moureau2016 ER - TY - JOUR AU - Gil Del Alcazar, C. R. AU - Todorova, P. K. AU - Habib, A. A. AU - Mukherjee, B. AU - Burma, S. PY - 2016 DA - 2016// TI - Augmented HR repair mediates acquired Temozolomide resistance in Glioblastoma JO - Mol Cancer Res VL - 14 UR - https://doi.org/10.1158/1541-7786.MCR-16-0125 DO - 10.1158/1541-7786.MCR-16-0125 ID - Gil Del Alcazar2016 ER - TY - JOUR AU - Sorensen, C. S. AU - Hansen, L. T. AU - Dziegielewski, J. AU - Syljuasen, R. G. AU - Lundin, C. AU - Bartek, J. AU - Helleday, T. PY - 2005 DA - 2005// TI - The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair JO - Nat Cell Biol VL - 7 UR - https://doi.org/10.1038/ncb1212 DO - 10.1038/ncb1212 ID - Sorensen2005 ER - TY - JOUR AU - Liu, Q. AU - Guntuku, S. AU - Cui, X. S. AU - Matsuoka, S. AU - Cortez, D. AU - Tamai, K. PY - 2000 DA - 2000// TI - Chk1 is an essential kinase that is regulated by Atr and required for the G (2)/M DNA damage checkpoint JO - Genes Dev VL - 14 UR - https://doi.org/10.1101/gad.840500 DO - 10.1101/gad.840500 ID - Liu2000 ER - TY - JOUR AU - Dillon, M. T. AU - Good, J. S. AU - Harrington, K. J. PY - 2014 DA - 2014// TI - Selective targeting of the G2/M cell cycle checkpoint to improve the therapeutic index of radiotherapy JO - Clin Oncol VL - 26 UR - https://doi.org/10.1016/j.clon.2014.01.009 DO - 10.1016/j.clon.2014.01.009 ID - Dillon2014 ER - TY - JOUR AU - Dai, Y. AU - Grant, S. PY - 2010 DA - 2010// TI - New insights into checkpoint kinase 1 in the DNA damage response signaling network JO - Clin Cancer Res VL - 16 UR - https://doi.org/10.1158/1078-0432.CCR-09-1029 DO - 10.1158/1078-0432.CCR-09-1029 ID - Dai2010 ER - TY - JOUR AU - Gonzalez Besteiro, M. A. AU - Gottifredi, V. PY - 2015 DA - 2015// TI - The fork and the kinase: a DNA replication tale from a CHK1 perspective JO - Mutat Res Rev Mutat Res VL - 763 UR - https://doi.org/10.1016/j.mrrev.2014.10.003 DO - 10.1016/j.mrrev.2014.10.003 ID - Gonzalez Besteiro2015 ER - TY - JOUR AU - Chen, Z. AU - Xiao, Z. AU - Gu, W. Z. AU - Xue, J. AU - Bui, M. H. AU - Kovar, P. PY - 2006 DA - 2006// TI - Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics JO - Int J Cancer VL - 119 UR - https://doi.org/10.1002/ijc.22198 DO - 10.1002/ijc.22198 ID - Chen2006 ER - TY - JOUR AU - Qiu, Z. AU - Oleinick, N. L. AU - Zhang, J. PY - 2018 DA - 2018// TI - ATR/CHK1 inhibitors and cancer therapy JO - Radiother Oncol VL - 126 UR - https://doi.org/10.1016/j.radonc.2017.09.043 DO - 10.1016/j.radonc.2017.09.043 ID - Qiu2018 ER - TY - JOUR AU - Walton, M. I. AU - Eve, P. D. AU - Hayes, A. AU - Valenti, M. AU - Haven, B. A. AU - Box, G. PY - 2010 DA - 2010// TI - The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106 JO - Mol Cancer Ther VL - 9 UR - https://doi.org/10.1158/1535-7163.MCT-09-0938 DO - 10.1158/1535-7163.MCT-09-0938 ID - Walton2010 ER - TY - JOUR AU - Reader, J. C. AU - Matthews, T. P. AU - Klair, S. AU - Cheung, K. M. AU - Scanlon, J. AU - Proisy, N. PY - 2011 DA - 2011// TI - Structure-guided evolution of potent and selective CHK1 inhibitors through scaffold morphing JO - J Med Chem. VL - 54 UR - https://doi.org/10.1021/jm2007326 DO - 10.1021/jm2007326 ID - Reader2011 ER - TY - JOUR AU - Touchefeu, Y. AU - Khan, A. A. AU - Borst, G. AU - Zaidi, S. H. AU - McLaughlin, M. AU - Roulstone, V. PY - 2013 DA - 2013// TI - Optimising measles virus-guided radiovirotherapy with external beam radiotherapy and specific checkpoint kinase 1 inhibition JO - Radiother Oncol. VL - 108 UR - https://doi.org/10.1016/j.radonc.2013.05.036 DO - 10.1016/j.radonc.2013.05.036 ID - Touchefeu2013 ER - TY - JOUR AU - Borst, G. R. AU - McLaughlin, M. AU - Kyula, J. N. AU - Neijenhuis, S. AU - Khan, A. AU - Good, J. PY - 2013 DA - 2013// TI - Targeted radiosensitization by the Chk1 inhibitor SAR-020106 JO - Int J Radiat Oncol Biol Phys. VL - 85 UR - https://doi.org/10.1016/j.ijrobp.2012.08.006 DO - 10.1016/j.ijrobp.2012.08.006 ID - Borst2013 ER - TY - JOUR AU - Hagemann, S. AU - Heil, O. AU - Lyko, F. AU - Brueckner, B. PY - 2011 DA - 2011// TI - Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0017388 DO - 10.1371/journal.pone.0017388 ID - Hagemann2011 ER - TY - JOUR AU - Patties, I. AU - Jahns, J. AU - Hildebrandt, G. AU - Kortmann, R. D. AU - Glasow, A. PY - 2009 DA - 2009// TI - Additive effects of 5-aza-2′-deoxycytidine and irradiation on clonogenic survival of human medulloblastoma cell lines JO - Strahlenther Onkol. VL - 185 UR - https://doi.org/10.1007/s00066-009-1956-1 DO - 10.1007/s00066-009-1956-1 ID - Patties2009 ER - TY - JOUR AU - Hoglund, A. AU - Nilsson, L. M. AU - Forshell, L. P. AU - Maclean, K. H. AU - Nilsson, J. A. PY - 2009 DA - 2009// TI - Myc sensitizes p53-deficient cancer cells to the DNA-damaging effects of the DNA methyltransferase inhibitor decitabine JO - Blood. VL - 113 UR - https://doi.org/10.1182/blood-2008-10-183475 DO - 10.1182/blood-2008-10-183475 ID - Hoglund2009 ER - TY - JOUR AU - Maes, K. AU - De, S. E. AU - Lemaire, M. AU - De, R. H. AU - Menu, E. AU - Van, V. E. PY - 2014 DA - 2014// TI - The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma JO - Oncotarget VL - 5 UR - https://doi.org/10.18632/oncotarget.1821 DO - 10.18632/oncotarget.1821 ID - Maes2014 ER - TY - JOUR AU - Deng, T. AU - Zhang, Y. PY - 2009 DA - 2009// TI - Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2′-deoxycytidine JO - Life Sci VL - 84 UR - https://doi.org/10.1016/j.lfs.2008.12.015 DO - 10.1016/j.lfs.2008.12.015 ID - Deng2009 ER - TY - JOUR AU - Noushmehr, H. AU - Weisenberger, D. J. AU - Diefes, K. AU - Phillips, H. S. AU - Pujara, K. AU - Berman, B. P. PY - 2010 DA - 2010// TI - Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma JO - Cancer Cell VL - 17 UR - https://doi.org/10.1016/j.ccr.2010.03.017 DO - 10.1016/j.ccr.2010.03.017 ID - Noushmehr2010 ER - TY - JOUR AU - Shinawi, T. AU - Hill, V. K. AU - Krex, D. AU - Schackert, G. AU - Gentle, D. AU - Morris, M. R. PY - 2013 DA - 2013// TI - DNA methylation profiles of long- and short-term glioblastoma survivors JO - Epigenetics. VL - 8 UR - https://doi.org/10.4161/epi.23398 DO - 10.4161/epi.23398 ID - Shinawi2013 ER - TY - JOUR AU - Oppermann, H. AU - Dietterle, J. AU - Purcz, K. AU - Morawski, M. AU - Eisenloffel, C. AU - Muller, W. PY - 2018 DA - 2018// TI - Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts JO - Cancer Cell Int VL - 18 UR - https://doi.org/10.1186/s12935-018-0611-2 DO - 10.1186/s12935-018-0611-2 ID - Oppermann2018 ER - TY - STD TI - Quillien V, Lavenu A, Ducray F, Joly MO, Chinot O, Fina F, et al. Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial. Oncotarget. 2016;7:61916–29. doi:https://doi.org/10.18632/oncotarget.11322. ID - ref30 ER - TY - JOUR AU - Encinas, J. M. AU - Enikolopov, G. PY - 2008 DA - 2008// TI - Identifying and quantitating neural stem and progenitor cells in the adult brain JO - Methods Cell Biol VL - 85 UR - https://doi.org/10.1016/S0091-679X(08)85011-X DO - 10.1016/S0091-679X(08)85011-X ID - Encinas2008 ER - TY - JOUR AU - Prager, I. AU - Patties, I. AU - Himmelbach, K. AU - Kendzia, E. AU - Merz, F. AU - Muller, K. PY - 2016 DA - 2016// TI - Dose-dependent short- and long-term effects of ionizing irradiation on neural stem cells in murine hippocampal tissue cultures: Neuroprotective potential of resveratrol JO - Brain Behav VL - 6 UR - https://doi.org/10.1002/brb3.548 DO - 10.1002/brb3.548 ID - Prager2016 ER - TY - JOUR AU - Gahwiler, B. H. AU - Capogna, M. AU - Debanne, D. AU - McKinney, R. A. AU - Thompson, S. M. PY - 1997 DA - 1997// TI - Organotypic slice cultures: a technique has come of age JO - Trends Neurosci VL - 20 UR - https://doi.org/10.1016/S0166-2236(97)01122-3 DO - 10.1016/S0166-2236(97)01122-3 ID - Gahwiler1997 ER - TY - JOUR AU - Patties, I. AU - Kortmann, R. D. AU - Menzel, F. AU - Glasow, A. PY - 2016 DA - 2016// TI - Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugs JO - J Exp Clin Cancer Res VL - 35 UR - https://doi.org/10.1186/s13046-016-0376-1 DO - 10.1186/s13046-016-0376-1 ID - Patties2016 ER - TY - JOUR AU - Oppermann, H. e. n. r. y. AU - Purcz, K. a. t. h. a. r. i. n. a. AU - Birkemeyer, C. l. a. u. d. i. a. AU - Baran-Schmidt, R. a. i. n. e. r. AU - Meixensberger, J. ü. r. g. e. n. AU - Gaunitz, F. r. a. n. k. PY - 2019 DA - 2019// TI - Carnosine’s inhibitory effect on glioblastoma cell growth is independent of its cleavage JO - Amino Acids VL - 51 UR - https://doi.org/10.1007/s00726-019-02713-6 DO - 10.1007/s00726-019-02713-6 ID - Oppermann2019 ER - TY - JOUR AU - Matthews, T. P. AU - Jones, A. M. AU - Collins, I. PY - 2013 DA - 2013// TI - Structure-based design, discovery and development of checkpoint kinase inhibitors as potential anticancer therapies JO - Expert Opin Drug Discov VL - 8 UR - https://doi.org/10.1517/17460441.2013.788496 DO - 10.1517/17460441.2013.788496 ID - Matthews2013 ER - TY - JOUR AU - Zhou, L. AU - Steller, H. PY - 2003 DA - 2003// TI - Distinct pathways mediate UV-induced apoptosis in Drosophila embryos JO - Dev Cell. VL - 4 UR - https://doi.org/10.1016/S1534-5807(03)00085-6 DO - 10.1016/S1534-5807(03)00085-6 ID - Zhou2003 ER - TY - JOUR AU - Urist, M. AU - Tanaka, T. AU - Poyurovsky, M. V. AU - Prives, C. PY - 2004 DA - 2004// TI - p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2 JO - Genes Dev VL - 18 UR - https://doi.org/10.1101/gad.1221004 DO - 10.1101/gad.1221004 ID - Urist2004 ER - TY - JOUR AU - Matt, S. AU - Hofmann, T. G. PY - 2016 DA - 2016// TI - The DNA damage-induced cell death response: a roadmap to kill cancer cells JO - Cell Mol Life Sci VL - 73 UR - https://doi.org/10.1007/s00018-016-2130-4 DO - 10.1007/s00018-016-2130-4 ID - Matt2016 ER - TY - JOUR AU - Syljuasen, R. G. AU - Sorensen, C. S. AU - Hansen, L. T. AU - Fugger, K. AU - Lundin, C. AU - Johansson, F. PY - 2005 DA - 2005// TI - Inhibition of human Chk1 increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage JO - Mol Cell Biol VL - 25 UR - https://doi.org/10.1128/MCB.25.9.3553-3562.2005 DO - 10.1128/MCB.25.9.3553-3562.2005 ID - Syljuasen2005 ER - TY - JOUR AU - Liaw, H. AU - Lee, D. AU - Myung, K. PY - 2011 DA - 2011// TI - DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange JO - PLos One VL - 6 UR - https://doi.org/10.1371/journal.pone.0021424 DO - 10.1371/journal.pone.0021424 ID - Liaw2011 ER - TY - JOUR AU - Bao, S. AU - Wu, Q. AU - McLendon, R. E. AU - Hao, Y. AU - Shi, Q. AU - Hjelmeland, A. B. PY - 2006 DA - 2006// TI - Glioma stem cells promote radioresistance by preferential activation of the DNA damage response JO - Nature. VL - 444 UR - https://doi.org/10.1038/nature05236 DO - 10.1038/nature05236 ID - Bao2006 ER - TY - JOUR AU - Kim, H. J. AU - Kim, J. H. AU - Chie, E. K. AU - Young, P. D. AU - Kim, I. A. AU - Kim, I. H. PY - 2012 DA - 2012// TI - DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity JO - Radiat Oncol. VL - 7 UR - https://doi.org/10.1186/1748-717X-7-39 DO - 10.1186/1748-717X-7-39 ID - Kim2012 ER - TY - JOUR AU - Moen, E. L. AU - Stark, A. L. AU - Zhang, W. AU - Dolan, M. E. AU - Godley, L. A. PY - 2014 DA - 2014// TI - The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide JO - Mol Cancer Ther VL - 13 UR - https://doi.org/10.1158/1535-7163.MCT-13-0924 DO - 10.1158/1535-7163.MCT-13-0924 ID - Moen2014 ER - TY - JOUR AU - Hientz, K. AU - Mohr, A. AU - Bhakta-Guha, D. AU - Efferth, T. PY - 2017 DA - 2017// TI - The role of p53 in cancer drug resistance and targeted chemotherapy JO - Oncotarget VL - 8 UR - https://doi.org/10.18632/oncotarget.13475 DO - 10.18632/oncotarget.13475 ID - Hientz2017 ER - TY - JOUR AU - Morgan, M. A. AU - Parsels, L. A. AU - Zhao, L. AU - Parsels, J. D. AU - Davis, M. A. AU - Hassan, M. C. PY - 2010 DA - 2010// TI - Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair JO - Cancer Res VL - 70 UR - https://doi.org/10.1158/0008-5472.CAN-09-3573 DO - 10.1158/0008-5472.CAN-09-3573 ID - Morgan2010 ER - TY - JOUR AU - Yan, S. AU - Sorrell, M. AU - Berman, Z. PY - 2014 DA - 2014// TI - Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress JO - Cell Mol Life Sci VL - 71 UR - https://doi.org/10.1007/s00018-014-1666-4 DO - 10.1007/s00018-014-1666-4 ID - Yan2014 ER - TY - JOUR AU - Kim, H. AU - Zheng, S. AU - Amini, S. S. AU - Virk, S. M. AU - Mikkelsen, T. AU - Brat, D. J. PY - 2015 DA - 2015// TI - Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution JO - Genome Res VL - 25 UR - https://doi.org/10.1101/gr.180612.114 DO - 10.1101/gr.180612.114 ID - Kim2015 ER - TY - JOUR AU - Ohgaki, H. AU - Kleihues, P. PY - 2007 DA - 2007// TI - Genetic pathways to primary and secondary glioblastoma JO - Am. J. Pathol VL - 170 UR - https://doi.org/10.2353/ajpath.2007.070011 DO - 10.2353/ajpath.2007.070011 ID - Ohgaki2007 ER - TY - JOUR AU - Jakovlevs, A. AU - Vanags, A. AU - Balodis, D. AU - Gardovskis, J. AU - Strumfa, I. PY - 2014 DA - 2014// TI - Heterogeneity of Ki-67 and p53 expression in Glioblastoma JO - Acta Chirurgica Latviensis VL - 14 UR - https://doi.org/10.2478/chilat-2014-0102 DO - 10.2478/chilat-2014-0102 ID - Jakovlevs2014 ER - TY - JOUR AU - Ren, Z. P. AU - Olofsson, T. AU - Qu, M. AU - Hesselager, G. AU - Soussi, T. AU - Kalimo, H. PY - 2007 DA - 2007// TI - Molecular genetic analysis of p53 intratumoral heterogeneity in human astrocytic brain tumors JO - J Neuropathol Exp Neurol. VL - 66 UR - https://doi.org/10.1097/nen.0b013e318156bc05 DO - 10.1097/nen.0b013e318156bc05 ID - Ren2007 ER - TY - JOUR AU - Aparicio, A. AU - Eads, C. A. AU - Leong, L. A. AU - Laird, P. W. AU - Newman, E. M. AU - Synold, T. W. PY - 2003 DA - 2003// TI - Phase I trial of continuous infusion 5-aza-2′-deoxycytidine JO - Cancer Chemother Pharmacol VL - 51 UR - https://doi.org/10.1007/s00280-002-0563-y DO - 10.1007/s00280-002-0563-y ID - Aparicio2003 ER - TY - STD TI - Jackson S, Weingart J, Nduom EK, Harfi TT, George RT, McAreavey D, et al. The effect of an adenosine A2A agonist on intra-tumoral concentrations of temozolomide in patients with recurrent glioblastoma. Fluids Barriers CNS. 2018;15:2. doi:https://doi.org/10.1186/s12987-017-0088-8. ID - ref53 ER - TY - JOUR AU - Walton, M. I. AU - Eve, P. D. AU - Hayes, A. AU - Valenti, M. R. AU - Haven Brandon, A. K. AU - Box, G. PY - 2012 DA - 2012// TI - CCT244747 is a novel potent and selective CHK1 inhibitor with oral efficacy alone and in combination with genotoxic anticancer drugs JO - Clin Cancer Res VL - 18 UR - https://doi.org/10.1158/1078-0432.CCR-12-1322 DO - 10.1158/1078-0432.CCR-12-1322 ID - Walton2012 ER - TY - JOUR AU - Patel, R. AU - Barker, H. E. AU - Kyula, J. AU - McLaughlin, M. AU - Dillon, M. T. AU - Schick, U. PY - 2017 DA - 2017// TI - An orally bioavailable Chk1 inhibitor, CCT244747, sensitizes bladder and head and neck cancer cell lines to radiation JO - Radiother Oncol. VL - 122 UR - https://doi.org/10.1016/j.radonc.2016.12.026 DO - 10.1016/j.radonc.2016.12.026 ID - Patel2017 ER - TY - JOUR AU - Turcan, S. AU - Fabius, A. W. AU - Borodovsky, A. AU - Pedraza, A. AU - Brennan, C. AU - Huse, J. PY - 2013 DA - 2013// TI - Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine JO - Oncotarget VL - 4 UR - https://doi.org/10.18632/oncotarget.1412 DO - 10.18632/oncotarget.1412 ID - Turcan2013 ER - TY - JOUR AU - Massey, A. J. PY - 2016 DA - 2016// TI - Inhibition of ATR-dependent feedback activation of Chk1 sensitises cancer cells to Chk1 inhibitor monotherapy JO - Cancer Lett VL - 383 UR - https://doi.org/10.1016/j.canlet.2016.09.024 DO - 10.1016/j.canlet.2016.09.024 ID - Massey2016 ER -