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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway

Fig. 6

JMJD2C promoted the metastasis of CRC cells in vivo. a-b HCT116-shRNA/NT, HCT116-shRNA/JMJD2C, HCT116-empty vector, and HCT116-JMJD2C+/+ cells were respectively injected into the tail vein of nude mice (n = 6). After 42 days, the lung metastases images were observed and quantified by LB983 NIGHTOWL II system. c Quantification of lung metastatic nodules from 6 mice subjected to the indicated treatments. d-e Immunohistochemical and quantitative analysis of JMJD2C proteins on consecutive tissue microarray slides of lung metastatic nodules from 6 mice subjected to the indicated treatments. *, P < 0.05; **, P < 0.01 (t test)

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