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Table 1 Association between KDM4C expression and clinicopathological variables of CRC patients

From: JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway

Variables Low KDM4C expression (n = 67) High KDM4C expression (n = 57) P
n (%) n (%)
Age
 > 65 13 (19.40) 10 (17.54) 0.8210
 ≤ 65 54 (80.60) 47 (82.46)  
Gender
 Male 39 (58.21) 39 (68.42) 0.2673
 Female 28 (41.79) 18 (31.58)  
Tumor site
 Rectum 37 (55.22) 36 (63.16) 0.4642
 Colon 30 (44.78) 21 (36.84)  
Tumor differentiation
 Well 20 (29.85) 19 (33.33) 0.7019
 Moderate + Poor 47 (70.15) 38 (66.67)  
TNM stage
 Stage II 35 (52.23) 12 (21.05) 0.0004**
 Stage III 32 (47.77) 45 (78.95)  
Lymph vascular invasion
 Positive 44 (65.67) 42 (73.68) 0.4347
 Negative 23 (34.33) 15 (26.32)  
Perineural invasion
 Positive 52 (77.61) 46 (80.70) 0.8253
 Negative 15 (22.39) 11 (19.30)  
Liver metastasis
 Positive 9 (13.43) 22 (38.60) 0.0017**
 Negative 58 (86.57) 35 (51.40)  
Lung metastasis
 Positive 1 (1.49) 8 (14.04) 0.0114*
 Negative 66 (98.51) 49 (85.96)  
  1. *, P < 0.05; **, P < 0.01