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Table 1 Association between KDM4C expression and clinicopathological variables of CRC patients

From: JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway

Variables

Low KDM4C expression (n = 67)

High KDM4C expression (n = 57)

P

n (%)

n (%)

Age

 > 65

13 (19.40)

10 (17.54)

0.8210

 ≤ 65

54 (80.60)

47 (82.46)

 

Gender

 Male

39 (58.21)

39 (68.42)

0.2673

 Female

28 (41.79)

18 (31.58)

 

Tumor site

 Rectum

37 (55.22)

36 (63.16)

0.4642

 Colon

30 (44.78)

21 (36.84)

 

Tumor differentiation

 Well

20 (29.85)

19 (33.33)

0.7019

 Moderate + Poor

47 (70.15)

38 (66.67)

 

TNM stage

 Stage II

35 (52.23)

12 (21.05)

0.0004**

 Stage III

32 (47.77)

45 (78.95)

 

Lymph vascular invasion

 Positive

44 (65.67)

42 (73.68)

0.4347

 Negative

23 (34.33)

15 (26.32)

 

Perineural invasion

 Positive

52 (77.61)

46 (80.70)

0.8253

 Negative

15 (22.39)

11 (19.30)

 

Liver metastasis

 Positive

9 (13.43)

22 (38.60)

0.0017**

 Negative

58 (86.57)

35 (51.40)

 

Lung metastasis

 Positive

1 (1.49)

8 (14.04)

0.0114*

 Negative

66 (98.51)

49 (85.96)

 
  1. *, P < 0.05; **, P < 0.01