Fig. 4

DNMT3b silencing reduces IL-6-induced OCT4 and forced OCT4 expression increases the DNMT1 in Hep3B cells. a Effect of DNMT3b silencing on the IL-6-induced OCT4 expression in Hep3B cells. b OCT4 and DNMT1 protein levels of the shCtrl.- or shDNMT3b Hep3B cells. c Effect of forced OCT4 expression on the protein levels of DNMT1, DNMT3a, and DNMT3b in Hep3B cells. d DNMT3b and OCT4 protein levels of the shCtrl.- or shDNMT1 Hep3B cells. Western blotting analysis. *P < 0.05, **P < 0.01, ***P < 0.001, ***P < 0.0001, student t test