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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Upregulation of CENPM promotes hepatocarcinogenesis through mutiple mechanisms

Fig. 2

CENPM was overexpressed in HCC and significantly associated with poor prognosis. a, b CENPM was upregulated in tumor compared with normal liver tissues in HCC samples from GSE45436 and GSE55092. c Expression levels of CENPM in HCC tissues were higher than corresponding non-tumor tissues via qRT-PCR of 68 pairs of HCC samples. d Differential expression of CENPM in tumor grades. e CENPM protein level in 8 pairs of human clinical HCC tumor samples and adajacent non-tumor specimens. f CENPM relative expression in HCC cell lines (SMMC7721, Hep3B, HepG2, HCCLM3, Huh7 and SK-Hep1) compared with the immortalized normal human hepatic cell (L02). g Typical images of immunohistochemistry (IHC) in 18 pairs of HCC tissues showing the protein expression of CENPM in HCC and adjacent nontumor tissues. h, i Kaplan-Meier analysis of overall survival and disease free survival in 364 HCC patients from the TCGA dataset. ***P < 0.001,T-Tumor; NT-Nontumor

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