Fig. 3
From: Upregulation of CENPM promotes hepatocarcinogenesis through mutiple mechanisms
Knock-down CENPM inhibited HCC proliferation, cell invasion and cell migration in vitro. a, b CENPM knockdown efficiency and overexpression efficiency were confirmed by qPCR and western blotting in HepG2, Huh7 and HCCLM3 cell lines. c Colony formation assay showed that CENPM suppressed or promoted cell proliferation both in CENPM-knockdown HepG2 and Huh7 cell lines or CENPM overexpressing HCCLM3 cell line. d, e Downregulation of CENPM in HepG2 and Huh7 cell lines inhibited cell invasion and migration and CENPM overexpression in HCCLM3 reversed these results. *P < 0.05, **P < 0.01, ***P < 0.001