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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: Upregulation of CENPM promotes hepatocarcinogenesis through mutiple mechanisms

Fig. 5

The carcinogenic effect of CENPM in vivo. a Representative images of tumor volume and tumors removed from nude mice implanted with shRNA-CENPM transfected HCCLM3 cells (n = 5) or control cells (n = 5). b, c Characteristic images of an orthotopic transplantation tumor model of HCC in nude mice,HE staining and PET/CT. d Xenografts were fixed, embedded in paraffin and stained with CENPM, Bax, cleaved caspase 3, Ki67 antibodies for analysis of tumor growth and apoptosis. **P < 0.01

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