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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Upregulation of CENPM promotes hepatocarcinogenesis through mutiple mechanisms

Fig. 6

HBx upregulated CENPM by targeting miR1270. a The heatmaps of partial differential expressed genes in GSE96851 and GSE38941. b CENPM was up-regulated in HBV-related liver tissues compared with normal tissues in GSE96851 and GSE38941. c miR-1270 was recognized as a post-transcriptional regulator of CENPM by microRNA target prediction programs. d Western blotting showed HBx stably expressed in Huh7 and HepG2 cell lines. e miR-1270 was downregulated by RT-qPCR in HBx stably expressing Huh7 and HepG2 cell lines. f Transfection of HBx resulted in upregulation of CENPM through miR-1270, as determined by PCR. *P < 0.05, **P < 0.01

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