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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: STRA6 exerts oncogenic role in gastric tumorigenesis by acting as a crucial target of miR-873

Fig. 7

miR-873 is downregulated in GC and play a tumour-suppressive role. a miR-873 was downregulated in GC tissues compared to adjacent normal tissues. b The correlation of expression between STRA6 and miR-873. c and d The effect of miR-873 on proliferation in GC cell were detected by Edu assay and colony formation assay. e and f STRA6 knockdown decreased cell migration ability of GC cells and upregulated expression of STRA6 reversed the effect. g and h The ability of migration and invasion of transfected cell were determined by Transwell migration and Matrigel invasion assays. (*p < 0.05, **p < 0.01, ***p < 0.001. The data expressed as the mean ± SD)

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