Fig. 7From: SIRT4 silencing in tumor-associated macrophages promotes HCC development via PPARδ signalling-mediated alternative activation of macrophagesSIRT4 interference in M2-like TAMs promotes H22 homograft development in BALB/c mice. a BALB/c mice were subcutaneously injected with shSIRT4-Lv-infected M2 (Ctr-Lv as control) along with H22 cells. Tumour weights are represented. Images are provided from each group. b The tumour size served as the measurement for H22 homograft development. c Summary data for each group are provided (n = 5). d Immunohistochemical staining of Ki67 in tumour sections (left). Summary data are shown on the right. *p < 0.05Back to article page