Table 1 Correlation expression of KIFC1 and clinicopathological parameters in 168 HCC cases in SYSUCC cohort
Variable | All cases (N = 168) | KIFC1 expression (%) | P values | |
|---|---|---|---|---|
|  | Low expression (N = 97) | High expression (N = 71) | ||
Age (years) | Â | Â | Â | 0.763 |
 ≤ 51 | 90 | 51 (56.7) | 39 (43.3) |  |
 > 51 | 78 | 46 (59.0) | 32 (41.0) |  |
Sex | Â | Â | Â | 0.849 |
 Male | 143 | 83 (58.0) | 60 (42.0) |  |
 Female | 25 | 14 (56.0) | 11 (44.0) |  |
AFP (ng/ml) | Â | Â | Â | 0.652 |
 ≤ 20 | 72 | 43 (59.7) | 29 (40.3) |  |
 > 20 | 96 | 54 (56.3) | 42 (43.7) |  |
HBsAg | Â | Â | Â | 0.394 |
 negative | 11 | 5 (45.5) | 6 (54.5) |  |
 positive | 157 | 92 (58.6) | 65 (41.4) |  |
Cirrhosis | Â | Â | Â | 0.713 |
 No | 99 | 56 (56.6) | 43 (43.4) |  |
 Yes | 69 | 41 (59.4) | 28 (40.6) |  |
Necrosis | Â | Â | Â | 0.506 |
 No | 76 | 46 (60.5) | 30 (39.5) |  |
 Yes | 92 | 51 (55.4) | 41 (44.6) |  |
Clinical stage | Â | Â | Â | 0.009 |
 I-II | 111 | 72 (64.9) | 39 (35.1) |  |
 III-IV | 57 | 25 (43.9) | 32 (56.1) |  |
Histologic grade (WHO) | Â | Â | Â | 0.113 |
 G1-G2 | 83 | 53 (63.9) | 30 (36.1) |  |
 G3-G4* | 85 | 44 (51.8) | 41 (48.2) |  |
Tumor size (cm) | Â | Â | Â | 0.031 |
 ≤ 5 | 73 | 49 (67.1) | 24 (32.9) |  |
 > 5 | 95 | 48 (50.5) | 47 (49.5) |  |
Tumor multiplicity | Â | Â | Â | 0.688 |
 Unifocal | 128 | 75 (58.6) | 53 (41.4) |  |
 Multifocal | 40 | 22 (55.0) | 18 (45.0) |  |
Intravascular emboli | Â | Â | Â | 0.688 |
 No | 100 | 59 (59.0) | 41 (41.0) |  |
 Yes | 68 | 38 (55.9) | 30 (44.1) |  |
Recurrence | Â | Â | Â | 0.037 |
 No | 125 | 78 (62.4) | 47 (37.6) |  |
 Yes | 43 | 19 (44.2) | 24 (55.8) |  |