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Table 1 Correlation expression of KIFC1 and clinicopathological parameters in 168 HCC cases in SYSUCC cohort

From: Correction to: KIFC1 is activated by TCF-4 and promotes hepatocellular carcinoma pathogenesis by regulating HMGA1 transcriptional activity

Variable All cases (N = 168) KIFC1 expression (%) P values
  Low expression (N = 97) High expression (N = 71)
Age (years)     0.763
 ≤ 51 90 51 (56.7) 39 (43.3)  
 > 51 78 46 (59.0) 32 (41.0)  
Sex     0.849
 Male 143 83 (58.0) 60 (42.0)  
 Female 25 14 (56.0) 11 (44.0)  
AFP (ng/ml)     0.652
 ≤ 20 72 43 (59.7) 29 (40.3)  
 > 20 96 54 (56.3) 42 (43.7)  
HBsAg     0.394
 negative 11 5 (45.5) 6 (54.5)  
 positive 157 92 (58.6) 65 (41.4)  
Cirrhosis     0.713
 No 99 56 (56.6) 43 (43.4)  
 Yes 69 41 (59.4) 28 (40.6)  
Necrosis     0.506
 No 76 46 (60.5) 30 (39.5)  
 Yes 92 51 (55.4) 41 (44.6)  
Clinical stage     0.009
 I-II 111 72 (64.9) 39 (35.1)  
 III-IV 57 25 (43.9) 32 (56.1)  
Histologic grade (WHO)     0.113
 G1-G2 83 53 (63.9) 30 (36.1)  
 G3-G4* 85 44 (51.8) 41 (48.2)  
Tumor size (cm)     0.031
 ≤ 5 73 49 (67.1) 24 (32.9)  
 > 5 95 48 (50.5) 47 (49.5)  
Tumor multiplicity     0.688
 Unifocal 128 75 (58.6) 53 (41.4)  
 Multifocal 40 22 (55.0) 18 (45.0)  
Intravascular emboli     0.688
 No 100 59 (59.0) 41 (41.0)  
 Yes 68 38 (55.9) 30 (44.1)  
Recurrence     0.037
 No 125 78 (62.4) 47 (37.6)  
 Yes 43 19 (44.2) 24 (55.8)  
  1. *:including 3 cases sarcomatoid liver cancer