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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: NOTCH2 negatively regulates metastasis and epithelial-Mesenchymal transition via TRAF6/AKT in nasopharyngeal carcinoma

Fig. 1

NOTCH2 downregulation is associated with poor prognosis in NPC. a Relative NOTCH2 protein expression in the non-metastatic and metastatic NPC tissues. Scale bar = 50 μm. b Relative NOTCH2 protein expression in the non-metastatic and metastatic NPC TMA (scale bar = 50 μm). c NOTCH2 staining intensity in the TMA samples from 117 patients with NPC. Data are the mean ± SD of at least three independent experiments; P-values were calculated using Student’s t-test. *P < 0.05. d Relative NOTCH2 and N2ICD protein expression in the NPC cell lines. Data are the mean ± SD of at least three independent experiments; statistical analysis was carried out using one-way analysis of variance. *P < 0.05. e TMA analyses of 117 patients with NPC diagnosed at the M0 stage. Kaplan–Meier OS curves for patients with NPC stratified by NOTCH2 expression

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